PAGE  1
000 A000000 06/30/2010
000 C000000 0001275617
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 COHEN & STEERS INFRASTRUCTURE  FUND INC.
001 B000000 811-021485
001 C000000 2128323232
002 A000000 280 PARK AVENUE
002 B000000 NEW YORK
002 C000000 NY
002 D010000 10017
003  000000 N
004  000000 N
005  000000 N
006  000000 N
007 A000000 N
007 B000000  0
007 C010100  1
008 A000001 COHEN & STEERS CAPITAL MANAGEMENT, INC.
008 B000001 A
008 C000001 801-27721
008 D010001 NEW YORK
008 D020001 NY
008 D030001 10017
010 A000001 COHEN & STEERS CAPITAL MANAGEMENT, INC.
010 B000001 801-27721
010 C010001 NEW YORK
010 C020001 NY
010 C030001 10017
010 A000002 STATE STREET BANK (SUB-ADMINISTRATOR)
010 B000002 85-05003
010 C010002 BOSTON
010 C020002 MA
010 C030002 02111
012 A000001 Bank of New York Mellon
012 B000001 85-05006
012 C010001 Jersey City
012 C020001 NJ
012 C030001 07310
013 A000001 PRICEWATERHOUSECOOPERS, LLP
013 B010001 NEW YORK
013 B020001 NY
013 B030001 10019
014 A000001 COHEN & STEERS SECURITIES, LLC
014 B000001 8-00
015 A000001 STATE STREET CORPORATION
      PAGE  2
015 B000001 C
015 C010001 BOSTON
015 C020001 MA
015 C030001 02111
015 C040001 8200
015 E010001 X
015 A000002 CITIBANK N.A.
015 B000002 S
015 C010002 BUENOS AIRES
015 D010002 ARGENTINA
015 E040002 X
015 A000003 UNICREDIT BANK AUSTRIA AG
015 B000003 S
015 C010003 VIENNA
015 D010003 AUSTRIA
015 E040003 X
015 A000004 THE HONGKONG AND SHANGHAI BANKING CORP. LTD.
015 B000004 S
015 C010004 SYDNEY
015 D010004 AUSTRALIA
015 E040004 X
015 A000005 HSBC BANK MIDDLE EAST LTD.
015 B000005 S
015 C010005 DUBAI
015 D010005 UNITED ARAB EMIRATES
015 E040005 X
015 A000006 DEUTSCHE BANK AG
015 B000006 S
015 C010006 BRUSSELS
015 D010006 BELGIUM
015 E040006 X
015 A000007 CITIBANK, N.A.
015 B000007 S
015 C010007 SAO PAULO
015 D010007 BRAZIL
015 E040007 X
015 A000008 STATE STREET TRUST COMPANY CANADA
015 B000008 S
015 C010008 TORONTO
015 D010008 CANADA
015 E040008 X
015 A000009 CLEARSTREAM BANKING SA
015 B000009 S
015 C010009 LUXEMBOURG
015 D010009 LUXEMBOURG
015 E040009 X
015 A000010 CREDIT SUISSE
015 B000010 S
015 C010010 ZURICH
015 D010010 SWITZERLAND
015 E040010 X
      PAGE  3
015 A000011 DEUTSCHE BANK AG
015 B000011 S
015 C010011 FRANKFURT
015 D010011 GERMANY
015 E040011 X
015 A000012 SKANDINAVISKA ENSKILDA BANKEN AB
015 B000012 S
015 C010012 COPENHAGEN
015 D010012 DENMARK
015 E040012 X
015 A000013 DEUTSCHE BANK S.A.E.
015 B000013 S
015 C010013 BARCELONA
015 D010013 SPAIN
015 E040013 X
015 A000014 SKANDINAVISKA ENSKILDA BANKEN AB (SEB)
015 B000014 S
015 C010014 HELSINKI
015 D010014 FINLAND
015 E040014 X
015 A000015 DEUTSCHE BANK AG
015 B000015 S
015 C010015 PARIS
015 D010015 FRANCE
015 E040015 X
015 A000016 STATE STREET BANK & TRUST CO.
015 B000016 S
015 C010016 LONDON
015 D010016 UNITED KINGDOM
015 E040016 X
015 A000017 BNP PARIBAS SECURITIES SERVICES, S.A.
015 B000017 S
015 C010017 ATHENS
015 D010017 GREECE
015 E040017 X
015 A000018 STANDARD CHARTERED BANK
015 B000018 S
015 C010018 HONG KONG
015 D010018 HONG KONG
015 E040018 X
015 A000019 Deutsche Bank S.p.A
015 B000019 S
015 C010019 MILAN
015 D010019 Italy
015 E040019 X
015 A000020 THE HONG KONG & SHANGHAI BANKING CORP., LTD.
015 B000020 S
015 C010020 Tokyo
015 D010020 Japan
015 E040020 X
015 A000021 THE HONG KONG & SHANGHAI BANKING CORP., LTD
      PAGE  4
015 B000021 S
015 C010021 SEOUL
015 D010021 REPUBLIC OF  KOREA
015 E040021 X
015 A000022 BANCO NACIONAL DE MEXICO S.A.
015 B000022 S
015 C010022 MEXICO CITY
015 D010022 MEXICO
015 E040022 X
015 A000023 STANDARD CHARTERED BANK MALAYSIA BERHAD
015 B000023 S
015 C010023 KUALA LUMPUR
015 D010023 MALAYSIA
015 E040023 X
015 A000024 DEUTSCHE BANK AG
015 B000024 S
015 C010024 AMSTERDAM
015 D010024 NETHERLANDS
015 E040024 X
015 A000025 SKANDINAVISKA ENSKILDA BANKEN AB
015 B000025 S
015 C010025 OSLO
015 D010025 NORWAY
015 E040025 X
015 A000026 THE HONGKONG AND SHANGHAI BANKING CORP LTD.
015 B000026 S
015 C010026 AUCKLAND
015 D010026 NEW ZEALAND
015 E040026 X
015 A000027 STANDARD CHARTERED BANK
015 B000027 S
015 C010027 MANILA
015 D010027 PHILIPPINES
015 E040027 X
015 A000028 BANK HANDLOWY W WARSZAWIE S.A.
015 B000028 S
015 C010028 WARSAW
015 D010028 POLAND
015 E040028 X
015 A000029 DEUTSCHE BANK AG
015 B000029 S
015 C010029 LISBON
015 D010029 PORTUGAL
015 E040029 X
015 A000030 SKANDINAVISKA ENSKILDA BANKEN AB
015 B000030 S
015 C010030 STOCKHOLM
015 D010030 SWEDEN
015 E040030 X
015 A000031 CITIBANK N.A.
015 B000031 S
      PAGE  5
015 C010031 SINGAPORE
015 D010031 SINGAPORE
015 E040031 X
015 A000032 STANDARD CHARTERED BANK (THAI) PUBLIC CO. LTD
015 B000032 S
015 C010032 BANGKOK
015 D010032 THAILAND
015 E040032 X
015 A000033 DEUTSCHE BANK AG
015 B000033 S
015 C010033 TAIPEI
015 D010033 TAIWAN
015 E040033 X
015 A000034 NEDBANK LTD.
015 B000034 S
015 C010034 JOHANNESBURG
015 D010034 SOUTH AFRICA
015 E040034 X
018  000000 Y
019 A000000 Y
019 B000000   21
019 C000000 COHENSTEER
020 A000001 MERRILL LYNCH PIERCE FENNER & SMITH, INC.
020 B000001 13-5674085
020 C000001    151
020 A000002 MORGAN STANLEY
020 B000002 13-2655998
020 C000002    121
020 A000003 J.P. MORGAN SECURITIES, INC.
020 B000003 13-3379014
020 C000003     95
020 A000004 CREDIT SUISSE SECURITIES (USA) LLC
020 B000004 13-5659485
020 C000004     94
020 A000005 BARCLAYS CAPITAL INC.
020 B000005 06-1031656
020 C000005     76
020 A000006 MACQUARIE SECURITIES (USA), INC.
020 B000006 98-0141094
020 C000006     71
020 A000007 GOLDMAN SACHS
020 B000007 15-5108880
020 C000007     67
020 A000008 UBS SECURITIES
020 B000008 13-3873456
020 C000008     58
020 A000009 NOMURA SECURITIES INTERNATIONAL, INC.
020 B000009 13-2642206
020 C000009     42
020 A000010 CITIGROUP GLOBAL
020 B000010 11-2418191
      PAGE  6
020 C000010     41
021  000000      946
022 A000001 STATE STR INSTL LIQUID RESVS FUND
022 C000001    127450
022 D000001    150276
022 A000002 FEDERATED GOVERNMENT OBLIGATIONS FUND
022 C000002    127450
022 D000002    150272
022 A000003 GOLDMAN SACHS & CO.
022 B000003 13-5108880
022 C000003      1770
022 D000003         0
023 C000000     256670
023 D000000     300547
024  000000 Y
025 A000001 BARCLAYS CAPITAL INC.
025 B000001 06-1031656
025 C000001 E
025 D000001   12435
025 A000002 J.P. MORGAN SECURITIES, INC.
025 B000002 13-3379014
025 C000002 E
025 D000002   16512
025 A000003 CITIGROUP GLOBAL MARKETS INC.
025 B000003 11-2418191
025 C000003 E
025 D000003   21038
026 A000000 N
026 B000000 Y
026 C000000 Y
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027  000000 N
028 A010000         0
028 A020000         0
028 A030000         0
028 A040000         0
028 B010000         0
028 B020000         0
028 B030000         0
028 B040000         0
028 C010000         0
028 C020000         0
028 C030000         0
028 C040000         0
028 D010000         0
028 D020000         0
      PAGE  7
028 D030000         0
028 D040000         0
028 E010000         0
028 E020000         0
028 E030000         0
028 E040000         0
028 F010000         0
028 F020000         0
028 F030000         0
028 F040000         0
028 G010000         0
028 G020000         0
028 G030000         0
028 G040000         0
028 H000000         0
030 A000000      0
030 B000000  0.00
030 C000000  0.00
031 A000000      0
031 B000000      0
032  000000      0
033  000000      0
035  000000      0
036 B000000      0
038  000000      0
042 A000000   0
042 B000000   0
042 C000000   0
042 D000000   0
042 E000000   0
042 F000000   0
042 G000000   0
042 H000000   0
043  000000      0
044  000000      0
045  000000 Y
046  000000 N
047  000000 Y
048  000000  0.850
048 A010000        0
048 A020000 0.000
048 B010000        0
048 B020000 0.000
048 C010000        0
048 C020000 0.000
048 D010000        0
048 D020000 0.000
048 E010000        0
048 E020000 0.000
048 F010000        0
048 F020000 0.000
      PAGE  8
048 G010000        0
048 G020000 0.000
048 H010000        0
048 H020000 0.000
048 I010000        0
048 I020000 0.000
048 J010000        0
048 J020000 0.000
048 K010000        0
048 K020000 0.000
049  000000 N
050  000000 N
051  000000 N
052  000000 N
053 A000000 Y
053 B000000 Y
053 C000000 N
054 A000000 Y
054 B000000 Y
054 C000000 N
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 Y
054 H000000 Y
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 N
054 M000000 Y
054 N000000 N
054 O000000 N
055 A000000 N
055 B000000 Y
056  000000 Y
057  000000 N
058 A000000 N
059  000000 Y
060 A000000 N
060 B000000 N
061  000000        0
062 A000000 N
062 B000000   0.0
062 C000000   0.0
062 D000000   0.0
062 E000000   0.0
062 F000000   0.0
062 G000000   0.0
062 H000000   0.0
062 I000000   0.0
062 J000000   0.0
      PAGE  9
062 K000000   0.0
062 L000000   0.0
062 M000000   0.0
062 N000000   0.0
062 O000000   0.0
062 P000000   0.0
062 Q000000   0.0
062 R000000   0.0
063 A000000   0
063 B000000  0.0
066 A000000 Y
066 B000000 N
066 C000000 N
066 D000000 N
066 E000000 N
066 F000000 N
066 G000000 Y
067  000000 N
068 A000000 N
068 B000000 N
069  000000 N
070 A010000 Y
070 A020000 N
070 B010000 Y
070 B020000 N
070 C010000 Y
070 C020000 N
070 D010000 Y
070 D020000 Y
070 E010000 Y
070 E020000 N
070 F010000 Y
070 F020000 N
070 G010000 Y
070 G020000 N
070 H010000 Y
070 H020000 N
070 I010000 N
070 I020000 N
070 J010000 Y
070 J020000 Y
070 K010000 Y
070 K020000 Y
070 L010000 Y
070 L020000 Y
070 M010000 Y
070 M020000 Y
070 N010000 Y
070 N020000 N
070 O010000 Y
070 O020000 Y
      PAGE  10
070 P010000 Y
070 P020000 N
070 Q010000 Y
070 Q020000 N
070 R010000 Y
070 R020000 N
071 A000000    565298
071 B000000    509053
071 C000000   1757645
071 D000000   29
072 A000000  6
072 B000000     8279
072 C000000    49442
072 D000000        0
072 E000000      123
072 F000000     7696
072 G000000      563
072 H000000        0
072 I000000       10
072 J000000      457
072 K000000        0
072 L000000      266
072 M000000       54
072 N000000        3
072 O000000        0
072 P000000     4544
072 Q000000        0
072 R000000       24
072 S000000      160
072 T000000        0
072 U000000        0
072 V000000        0
072 W000000      122
072 X000000    13899
072 Y000000     1077
072 Z000000    45022
072AA000000    40450
072BB000000    33186
072CC010000        0
072CC020000   210862
072DD010000    31170
072DD020000        0
072EE000000        0
073 A010000   0.4800
073 A020000   0.0000
073 B000000   0.0000
073 C000000   0.0000
074 A000000     8194
074 B000000        0
074 C000000        0
074 D000000    37574
      PAGE  11
074 E000000   466171
074 F000000  1635474
074 G000000        0
074 H000000        0
074 I000000    22231
074 J000000    16507
074 K000000        0
074 L000000    13237
074 M000000      160
074 N000000  2199548
074 O000000    10600
074 P000000     1425
074 Q000000   841000
074 R010000        0
074 R020000        0
074 R030000      144
074 R040000    32242
074 S000000        0
074 T000000  1314137
074 U010000    86335
074 U020000        0
074 V010000    15.22
074 V020000     0.00
074 W000000   0.0000
074 X000000    60420
074 Y000000  1737963
075 A000000        0
075 B000000  1825780
076  000000    12.65
077 A000000 Y
077 B000000 N
077 C000000 Y
077 D000000 N
077 E000000 N
077 F000000 N
077 G000000 N
077 H000000 N
077 I000000 Y
077 J000000 N
077 K000000 N
077 L000000 N
077 M000000 Y
077 N000000 N
077 O000000 N
077 P000000 N
077 Q010000 Y
077 Q020000 N
077 Q030000 N
078  000000 N
080 C000000        0
081 B000000   0
      PAGE  12
082 B000000        0
083 B000000        0
084 B000000        0
086 A010000  43235
086 A020000 753236
086 B010000    221
086 B020000   2840
086 C010000      0
086 C020000      0
086 D010000      0
086 D020000      0
086 E010000      0
086 E020000      0
086 F010000      0
086 F020000      0
087 A010000 COMMON STOCK
087 A020000 19248A109
087 A030000 UTF
088 A000000 N
088 B000000 N
088 C000000 N
088 D000000 N
SIGNATURE   LESTER LAY
TITLE       VICE PRESIDENT