SCHEDULE 14A INFORMATION
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OMEROS CORPORATION
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April 22, 2016
Dear Fellow Shareholder:
You are cordially invited to attend the 2016 Annual Meeting of Shareholders of Omeros Corporation. The meeting will be held at the World Trade Center Seattle located at 2200 Alaskan Way, Suite 410, Seattle, Washington 98121, on Thursday, June 9, 2016, at 10:00 a.m. local time.
The attached Notice of Annual Meeting of Shareholders and Proxy Statement contain details of the business to be conducted at the annual meeting.
Whether or not you attend the annual meeting, it is important that your shares be represented and voted. Therefore, please vote as soon as possible by telephone, via the Internet or by completing and mailing the enclosed proxy card. Voting by any of these methods will ensure your representation at the annual meeting. If you decide to attend the annual meeting, you will be able to vote in person even if you have previously submitted your proxy.
On behalf of our Board of Directors, I would like to express our appreciation for your continued support of Omeros. We look forward to seeing you at the annual meeting.
Sincerely, |
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GREGORY A. DEMOPULOS, M.D. Chairman and CEO |
NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
TO BE HELD ON JUNE 9, 2016
April 22, 2016
To the Shareholders:
We cordially invite you to the 2016 Annual Meeting of Shareholders, or the 2016 Annual Meeting, of Omeros Corporation, a Washington corporation, to be held on Thursday, June 9, 2016, at 10:00 a.m. local time at the World Trade Center Seattle, 2200 Alaskan Way, Suite 410, Seattle, Washington 98121, for the following purposes:
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to elect the three Class I director nominees named in this proxy statement to the board of directors, each to serve until the 2019 Annual Meeting of Shareholders; |
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to ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2016; and |
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to transact such other business as may properly come before the 2016 Annual Meeting or any adjournment or postponement of the 2016 Annual Meeting. |
The foregoing items of business are more fully described in the proxy statement accompanying this notice.
Shareholders of record at the close of business on April 12, 2016 will be entitled to vote at the 2016 Annual Meeting and at any adjournment or postponement of the meeting.
The proxy statement accompanying this notice is being issued in connection with the solicitation by the board of directors of a proxy on the enclosed form of proxy card for use at the 2016 Annual Meeting.
We look forward to seeing you at the 2016 Annual Meeting.
By Order of the Board of Directors, |
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Marcia S. Kelbon Vice President, Patent General Counsel and Secretary |
YOUR VOTE IS IMPORTANT
Whether or not you plan to attend the 2016 Annual Meeting, we encourage you to vote in advance of the meeting to assure your representation at the meeting. You may vote prior to the 2016 Annual Meeting by mailing the proxy card in the enclosed postage-prepaid envelope, by telephone or via the Internet in accordance with the instructions on your proxy card. Even if you vote in advance of the 2016 Annual Meeting, you may still vote in person if you attend the meeting. Please note, however, that if your shares are held of record by a broker, bank or other nominee and you wish to vote at the 2016 Annual Meeting, you must obtain from the record holder a proxy card issued in your name.
IMPORTANT NOTICE REGARDING THE AVAILABILITY OF PROXY MATERIALS FOR THE 2016 ANNUAL MEETING OF SHAREHOLDERS TO BE HELD ON JUNE 9, 2016 |
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The proxy statement and the 2015 Annual Report to Shareholders are available at: www.edocumentview.com/OMER. |
The Omeros Building
201 Elliott Avenue West
Seattle, WA 98119
PROXY STATEMENT FOR 2016 ANNUAL MEETING OF SHAREHOLDERS
INFORMATION CONCERNING PROXY SOLICITATION, VOTING AND THE MEETING
General
The enclosed proxy is solicited on behalf of the board of directors of Omeros Corporation for use at the 2016 Annual Meeting of Shareholders, or the 2016 Annual Meeting, of Omeros Corporation to be held on Thursday, June 9, 2016, at 10:00 a.m., local time, or at any adjournment or postponement thereof, for the purposes set forth herein and in the accompanying Notice of Annual Meeting of Shareholders. The 2016 Annual Meeting will be held at the World Trade Center Seattle, 2200 Alaskan Way, Suite 410, Seattle, Washington 98121.
These proxy solicitation materials and the 2015 Annual Report to Shareholders, which includes audited financial statements as of and for the year ended December 31, 2015, were mailed on or about April 22, 2016 to all shareholders entitled to vote at the 2016 Annual Meeting.
Record Date and Quorum
Shareholders of record at the close of business on April 12, 2016, which we refer to as the record date, are entitled to notice of and to vote their shares at the 2016 Annual Meeting. At the record date, 39,119,154 shares of Omeros’ common stock, $0.01 par value per share, were issued and outstanding. Holders of shares of common stock are entitled to cast one vote per share on all matters to be voted upon at the 2016 Annual Meeting. The presence in person or by proxy of the holders of record of a majority of the outstanding shares of common stock entitled to vote is required to constitute a quorum for the transaction of business at the 2016 Annual Meeting.
Abstentions and broker non-votes (which occur when a broker indicates on a proxy card that it is not voting on a matter) are considered shares present at the 2016 Annual Meeting for the purpose of determining a quorum. The inspector of elections, Computershare Inc., will determine whether or not a quorum is present at the 2016 Annual Meeting.
Proposals at the 2016 Annual Meeting
Shareholders are being asked to vote on the following proposals:
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Proposal 1. The election of the three Class I director nominees named in this proxy statement to the board of directors, each to serve until our 2019 Annual Meeting of Shareholders; |
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Proposal 2. The ratification of the appointment of Ernst & Young LLP, or Ernst & Young, as our independent registered public accounting firm for the fiscal year ending December 31, 2016; and |
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Any other business that may properly come before the 2016 Annual Meeting or any adjournment or postponement of the meeting. |
Our board of directors recommends you vote:
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“FOR” the election of each of the Class I director nominees named in this proxy statement; and |
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“FOR” the ratification of the appointment of Ernst & Young as our independent registered public accounting firm for the fiscal year ending December 31, 2016. |
Votes Required
Proposal 1: Election of Directors
The three candidates for director who receive the highest number of affirmative votes will be elected. Shareholders are not entitled to cumulate votes for the election of directors.
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Proposal 2: Ratification of Appointment of Independent Registered Public Accounting Firm
Ratification of the appointment of Ernst & Young as our independent registered public accounting firm will occur if the number of votes cast in favor of this proposal exceeds the number of votes cast against this proposal.
Abstentions and Broker Non-Votes
Abstentions will not be counted as votes cast in favor of or against either proposal. Accordingly, abstentions will not affect the determination of the directors who have received the highest number of affirmative votes or whether the votes cast in favor of Proposal 2 exceed those cast against the proposal.
Brokers and other intermediaries who hold shares for the accounts of their clients may vote such shares either as directed by their clients or, in the case of “uninstructed shares,” in their own discretion if permitted by the stock exchange or other organization of which they are members. Certain types of proposals are considered “non-discretionary” under stock exchange regulations, however, and brokers who have received no instructions from their clients do not have discretion to vote such uninstructed shares on those items. At the 2016 Annual Meeting, brokers will not have discretion to vote uninstructed shares on Proposal 1, but will have discretion to vote uninstructed shares on Proposal 2. Uninstructed shares for which brokers or other intermediaries lack voting discretion are referred to as “broker non-votes.” Broker non-votes will not be counted as votes cast for or against either proposal.
Brokers will not have discretion to vote uninstructed shares with respect to the election of directors. Broker non-votes received on Proposal 1 will not affect the determination of the directors who have received the highest number of affirmative votes. Brokers will be permitted to vote uninstructed shares in their discretion with respect to ratification of the appointment of an independent registered public accounting firm, so we do not expect to receive broker non-votes on Proposal 2. Brokers will have similar discretion to vote on any other routine proposals brought before the 2016 Annual Meeting.
How to Vote
If your shares are registered directly in your name with our transfer agent, Computershare Inc., you are considered the registered shareholder of those shares. Registered shareholders may cast their vote by:
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signing, dating and promptly mailing the proxy card in the enclosed postage-paid envelope; |
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calling 1-800-652-VOTE (8683) using a touch-tone telephone; |
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accessing the Internet website www.envisionreports.com/OMER; or |
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completing a ballot at the 2016 Annual Meeting. |
If your shares are held in the name of a brokerage firm or bank or other similar organization, you are considered the beneficial shareholder with respect to those shares. If you are a beneficial shareholder, please refer to your proxy card or the information forwarded by your broker, bank or other holder of record to see what options are available to you to cast your vote. A beneficial shareholder may not vote shares in person at the 2016 Annual Meeting unless he or she obtains a “legal proxy” from the broker, bank or other holder of record that holds his or her shares.
Whether or not you plan to attend the 2016 Annual Meeting, we encourage you to vote in advance of the meeting to assure your representation at the meeting. Votes cast by proxy or in person at the 2016 Annual Meeting will be tabulated by the inspector of elections appointed for the meeting.
Revoking a Proxy
A registered shareholder can revoke his or her proxy before the time of voting at the 2016 Annual Meeting by any of the following:
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mailing a revised proxy card dated later than the prior proxy card; |
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submitting a new vote by telephone; |
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submitting a new vote via the Internet; |
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voting in person at the 2016 Annual Meeting; or |
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notifying our corporate secretary in writing that he or she is revoking the proxy. The revocation must be received before the 2016 Annual Meeting to be effective. |
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Any beneficial shareholder may change or revoke his or her voting instructions by contacting the broker, bank or other nominee holding the shares or by obtaining a proxy from such institution and voting in person at the 2016 Annual Meeting.
Attending the 2016 Annual Meeting
Only shareholders as of the close of business on April 12, 2016 (the record date), or holders of a valid proxy for the meeting, are entitled to attend the 2016 Annual Meeting. In order to gain admittance to the meeting, you may be asked to present photo identification, such as a driver’s license or passport, and proof of stock ownership as of the record date, such as a brokerage statement or letter from a bank or broker indicating beneficial ownership on the record date. We will be unable to admit anyone who does not present acceptable identification upon request or refuses to comply with our admittance and security procedures. Use of cameras, recording devices and other electronic devices is prohibited at the meeting.
How to Obtain Directions to Attend the 2016 Annual Meeting
The 2016 Annual Meeting will be held on Thursday, June 9, 2016, at 10:00 a.m., local time, at the World Trade Center Seattle, 2200 Alaskan Way, Suite 410, Seattle, Washington 98121. If you need directions to the meeting, please call Omeros’ investor relations department at (206) 676-5000. Information on how to vote in person at the 2016 Annual Meeting is discussed above.
Proxy Solicitation
This proxy statement is furnished in connection with the solicitation of your vote by the board of directors. We pay the costs of soliciting proxies from our shareholders. We may reimburse brokerage firms and other persons representing beneficial shareholders for their expenses in forwarding the voting materials to the beneficial shareholders. Directors, officers and regular employees may solicit proxies on our behalf personally, by telephone or by facsimile without additional compensation. Currently, we do not intend to retain any person to assist in the solicitation of proxies.
“Householding” of Proxy Materials
A copy of our 2015 Annual Report to Shareholders, including our 2015 Annual Report on Form 10-K, accompanies this proxy statement. If you are a beneficial shareholder, your bank or broker may deliver a single proxy statement and 2015 Annual Report to Shareholders, along with individual proxy cards or voting instruction forms, to any household at which two or more beneficial shareholders reside unless contrary instructions have been received from you. This procedure, referred to as householding, reduces the volume of duplicate materials shareholders receive and reduces mailing expenses. If you would like to revoke your consent to householding and in the future receive your own set of proxy materials, or if your household is currently receiving multiple copies of the same items and you would like in the future to receive only a single copy at your address, you should contact your bank, broker or other nominee. Alternatively, you may also contact our corporate secretary at (206) 676-5000 or send a written request to our corporate secretary at The Omeros Building, 201 Elliott Avenue West, Seattle, Washington 98119 to revoke your consent to householding or to receive a separate proxy statement and 2015 Annual Report to Shareholders.
Shareholder Proposals for 2017 Annual Meeting
Under Rule 14a-8 under the Securities Exchange Act of 1934, or the Exchange Act, we must receive shareholder proposals intended for inclusion in our proxy statement for our 2017 Annual Meeting of Shareholders, or the 2017 Annual Meeting, at our principal executive offices at The Omeros Building, 201 Elliott Avenue West, Seattle, Washington 98119, by the close of business on or prior to December 23, 2016. However, if the date of the 2017 Annual Meeting changes by more than 30 days from the date of the 2016 Annual Meeting, notice by a shareholder of a proposal must be received a reasonable time before we begin to print and send the proxy materials for the 2017 Annual Meeting.
We must receive shareholder proposals submitted for consideration at the 2017 Annual Meeting, but not for inclusion in our proxy statement for the 2017 Annual Meeting under Exchange Act Rule 14a-8, and director nominations at our principal executive offices at The Omeros Building, 201 Elliott Avenue West, Seattle, Washington 98119, by the close of business on or prior to December 23, 2016. However, if the date of the 2017 Annual Meeting changes by more than 30 days from the date of the 2016 Annual Meeting, notice by a shareholder of a proposal or a director nomination must be received no later than the close of business on the later of (1) 120 calendar days in advance of the 2017 Annual Meeting and (2) 10 calendar days following the date on which public announcement of the date of the 2017 Annual Meeting is first made.
In addition, notice of any shareholder proposal or director nomination must be given in accordance with our bylaws and the applicable requirements of Rule 14a-8 under the Exchange Act. If a shareholder fails to give notice of a proposal as required by our bylaws or other applicable requirements, then the proposal will not be included in the proxy statement for the 2017 Annual Meeting and the shareholder will not be permitted to present the proposal for a vote at the 2017 Annual Meeting.
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PROPOSAL 1 — ELECTION OF DIRECTORS
In accordance with our bylaws, our board of directors has set its size at seven members. Our board is divided into three classes serving staggered three-year terms. The terms of our directors will expire as set forth in the following table:
Omeros Board of Directors |
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Term Expires |
Class I Directors |
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Ray Aspiri |
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2016 |
Arnold C. Hanish |
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2016 |
Rajiv Shah, M.D. |
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2016 |
Class II Directors |
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Thomas J. Cable |
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2017 |
Peter A. Demopulos, M.D., FACC, FSCAI |
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2017 |
Class III Directors |
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Gregory A. Demopulos, M.D. |
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2018 |
Leroy E. Hood, M.D., Ph.D. |
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2018 |
Following the recommendation of the nominating and governance committee, our board of directors has nominated each of our current Class I directors for election at the 2016 Annual Meeting. If elected, each of Mr. Aspiri, Mr. Hanish and Dr. Shah would serve until the 2019 Annual Meeting of Shareholders and until his successor is duly elected and qualified, or until his earlier death, resignation or removal.
Nominees for Election as Class I Directors
Set forth below is biographical information for each person nominated for election at the 2016 Annual Meeting for a term expiring at the 2019 Annual Meeting of Shareholders.
Ray Aspiri, age 79, has served on our board of directors since January 1995 and previously served as our treasurer from January 1999 to September 2007. Mr. Aspiri has also served as chairman of our compensation committee since January 1995 and as a member of our nominating and governance and audit committees since September 2009 and July 2011, respectively. From his founding of the company in 1997 until its sale in December 2012, Mr. Aspiri served as the chairman of the board of Tempress Technologies, Inc., a privately held research and development company that specialized in high-pressure fluid dynamics for the oil and gas industry. From 1980 to 1997, Mr. Aspiri served as the chairman of the board and chief executive officer of Tempress, Inc., a privately held company specializing in products for the truck, marine and sporting goods industries. Our nominating and governance committee has concluded that Mr. Aspiri should continue to serve on the board of directors based on his experience in founding and managing companies, his knowledge of commercial manufacturing and his prior experience serving on our board of directors and as chairman of our compensation committee. Mr. Aspiri has indicated an interest in potentially retiring from the board of directors before the conclusion of the term expiring at the 2019 Annual Meeting of Shareholders and has requested that we continue our ongoing search for additional director candidates to potentially replace Mr. Aspiri should he elect to retire from our board of directors prior to the expiration of the term for which he has been nominated.
Arnold C. Hanish, age 68, has served on our board of directors and as chairman of our audit committee since September 2012. From 1994 until his retirement in December 2012, Mr. Hanish served as vice president and chief accounting officer at Eli Lilly and Company. Prior to his appointment as chief accounting officer, Mr. Hanish held a number of senior financial positions at Eli Lilly. Before Eli Lilly, Mr. Hanish held various positions at Arthur Young & Company (currently Ernst & Young) for nearly 14 years. Mr. Hanish currently is a member of the Deloitte and Touche Audit Quality Review Council. Mr. Hanish was a member of the Standing Advisory Group of the Public Company Accounting Oversight Board from 2004 through 2008 and from 2011 through 2012. In addition, from 2007 to 2010, he served as the chairperson of Financial Executives International’s Committee on Corporate Reporting. Mr. Hanish earned his B.A. in accounting from the University of Cincinnati. Our nominating and governance committee has concluded that Mr. Hanish should continue to serve on the board of directors based on his experience in public company finance and accounting, SEC reporting, management and corporate governance, his knowledge of the pharmaceutical and biotechnology industry and his experience as the chairman of our audit committee.
Rajiv Shah, M.D., age 43, has served on our board of directors since June 2015. Dr. Shah is the founder and managing partner of Latitude Capital, an emerging markets private equity firm, and is a Distinguished Fellow at Georgetown University’s School of Foreign Service. Dr. Shah served as Administrator of the United States Agency for International Development, or USAID, from January 2010 to February 2015. Prior to his appointment at USAID, Dr. Shah served as Undersecretary and Chief Scientist at the U.S. Department of Agriculture from May 2009 to December 2009, during which time he created the National Institute for Food and Agriculture. Prior to working in government, Dr. Shah worked in senior roles at the Bill & Melinda Gates Foundation, leading the Foundation's efforts in global health, agriculture and financial services. Dr. Shah also serves on the board of directors of Arcadia
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Biosciences, Inc., a publicly traded agricultural technology company, and the board of trustees of the Rockefeller Foundation. Dr. Shah earned his M.D. from the University of Pennsylvania Medical School, his Master of Science in Health Economics at the Wharton School of Business and his Bachelor of Science in Economics from the University of Michigan. Our nominating and governance committee has concluded that Dr. Shah should continue to serve on the board of directors based on his experience in government, regulatory affairs, international development and strategic partnerships, as well as his scientific background.
THE BOARD OF DIRECTORS RECOMMENDS THAT SHAREHOLDERS
VOTE FOR ALL OF THE NOMINEES NAMED ABOVE
Class II Directors — Continuing in Office until the 2017 Annual Meeting of Shareholders
Thomas J. Cable, age 76, has served on our board of directors since January 1995. He has also served on our audit committee since January 1995 and on our compensation committee since December 2007. In addition, Mr. Cable has served as chairman of our nominating and governance committee since September 2009. Mr. Cable is the vice chairman of the board of the Washington Research Foundation, a technology transfer and early stage venture capital organization affiliated with the University of Washington, which he co-founded in 1980. Mr. Cable also founded Cable & Howse Ventures, a venture capital firm, and Cable, Howse & Ragen, an investment banking firm, and co-founded Montgomery Securities, an investment banking firm acquired by Bank of America. A former U.S. Navy submarine officer, Mr. Cable received his M.B.A. from the Stanford Graduate School of Business and his B.A. from Harvard University. Our nominating and governance committee has concluded that Mr. Cable should continue to serve on the board of directors based on his knowledge and experience in finance, investment banking, technology development and product commercialization, as well as his knowledge of Omeros and our industry.
Peter A. Demopulos, M.D., FACC, FSCAI, age 62, has served on our board of directors since January 1995. Dr. Demopulos is a practicing board-certified general and interventional cardiologist at Seattle Cardiology, part of the Swedish Heart & Vascular Institute. He has been a member of Seattle Cardiology since 2005, also serving as its Medical Director from 2005 to 2010. Dr. Demopulos is also a clinical assistant professor of cardiology at the University of Washington School of Medicine, a position that he has held since 1989. He participates as an investigator in clinical trials evaluating interventional cardiology devices and drug therapies at Seattle Cardiovascular Research and Swedish Cardiovascular Research. Dr. Demopulos received his M.D. from the Stanford University School of Medicine and his B.S. from Stanford University. Our nominating and governance committee has concluded that Dr. Demopulos should continue to serve on the board of directors based on his medical and scientific expertise, his experience as a clinical investigator in relevant therapeutic areas and his experience with clinical development and trial design, as well as his knowledge of Omeros and our industry. Dr. Demopulos is the brother of Gregory A. Demopulos, M.D., our president and chief executive officer and the chairman of our board of directors.
Class III Directors — Continuing in Office until the 2018 Annual Meeting of Shareholders
Gregory A. Demopulos, M.D., age 57, founded our company and has served as our president, chief executive officer and chairman of the board of directors since June 1994. In an interim capacity, he also served as our chief financial officer and treasurer from January 2009 to October 2013 and as our chief medical officer from June 1994 to March 2010. Prior to founding Omeros, Dr. Demopulos completed his residency in orthopedic surgery at Stanford University and his fellowship training in hand and microvascular surgery at Duke University. Dr. Demopulos currently serves on the board of trustees of the Smead Funds Trust, an open-end mutual fund company registered under the Investment Company Act of 1940, and on the board of directors of Onconome, Inc., a privately held company developing biomarkers for early cancer detection. His non-profit service includes the Seattle Community Development Round Table and the Northwest NeuroNeighborhood board of directors. Dr. Demopulos received his M.D. from the Stanford University School of Medicine and his B.S. from Stanford University. Our nominating and governance committee has concluded that Dr. Demopulos should continue to serve on the board of directors based on his position and experience as our chief executive officer and his medical and scientific expertise, experience with clinical development and design and knowledge of our operations and development programs. Dr. Demopulos is the brother of Peter A. Demopulos, M.D., a member of our board of directors.
Leroy E. Hood, M.D., Ph.D., age 77, has served on our board of directors since March 2001. He also has served on our nominating and governance committee since September 2009 and on our compensation committee since July 2011. Dr. Hood previously served as a member of our audit committee from September 2009 to December 2009 and from June 2012 to September 2012. Dr. Hood is the president of the Institute for Systems Biology, a non-profit research institute dedicated to the study and application of systems biology, which he co-founded in 2000, and has served as senior vice president and chief science officer of Providence Health & Services, a multi-state, not-for-profit health system, since April 2016. Previously, Dr. Hood was founder and chairman of the Department of Molecular Biotechnology at the University of Washington School of Medicine. Dr. Hood also co-founded Amgen, Inc., Applied Biosystems, Inc., Darwin Molecular Technologies, Inc., Rosetta Inpharmatics, Inc. and SyStemix, Inc. Dr. Hood is a member of the National Academy of Sciences, the American Philosophical Society, the American Association of Arts and Sciences, the Institute of Medicine and the National Academy of Engineering. Dr. Hood received his Ph.D. and B.S. from the California Institute of Technology and his M.D. from The Johns Hopkins School of Medicine. Our nominating and governance
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committee has concluded that Dr. Hood should continue to serve on the board of directors based on his scientific expertise in drug discovery and development and experience in founding and building biotechnology and pharmaceutical companies.
Board Leadership Structure
Gregory A. Demopulos, M.D., is our principal executive officer and chairman of the board of directors. Thomas J. Cable is our lead independent director. The responsibilities of our lead independent director are to:
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serve as chairman of meetings of the board of directors at which the chairman of the board is not present, such as executive sessions of the non-executive directors; |
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call meetings of the non-executive directors as he deems appropriate; |
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serve as the principal liaison on board-wide issues between the chairman of the board and the non-executive directors; and |
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coordinate the activities of the non-executive directors as he deems appropriate. |
Taking into account Dr. Demopulos’ in-depth knowledge of our operations, programs and strategy, as well as the oversight authority granted to our lead independent director and the committees of our board of directors, which are each comprised solely of independent directors, our board of directors has determined that combining the principal executive officer and chairman of the board of directors positions and appointing a separate lead independent director is the appropriate board leadership structure for us at this time.
Risk Oversight
Our management is primarily responsible for assessing and managing risk, while our board of directors is responsible for overseeing management’s execution of its responsibilities. The board of directors is supported by its committees in fulfillment of this responsibility. In particular, the audit committee focuses on our overall financial risk by evaluating our internal controls and disclosure policies, as well as the integrity of our financial statements and periodic reports. Our compensation committee strives to create incentives that encourage a reasonable and appropriate level of risk-taking consistent with our business strategy. Finally, the nominating and governance committee is responsible for reviewing our corporate governance and developing and maintaining corporate governance policies and procedures that are appropriate in light of the risks we face.
Director Independence
Our board of directors has determined that Mr. Aspiri, Mr. Cable, Mr. Hanish, Dr. Hood and Dr. Shah each meet the independence requirements under applicable listing standards of The Nasdaq Stock Market, or Nasdaq, as well as applicable rules promulgated by the Securities and Exchange Commission, or SEC.
Board and Committee Meeting and Annual Meeting Attendance
Our board of directors held a total of seven meetings during 2015. No director attended fewer than 75% of the total number of board meetings and the total number of committee meetings of the board on which he served during 2015 for the period that he was a director or committee member, with the exception of Dr. Hood who attended 53% (8 of 15) of such meetings. We encourage, but do not require, our board members to attend our annual meetings of shareholders. Four of the six directors then serving on our board attended our 2015 Annual Meeting of Shareholders.
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Committees of the Board of Directors
Our board of directors has standing audit, compensation and nominating and governance committees, each of which has the composition and responsibilities described below. The following table provides membership information for each committee during 2015:
Chair Member
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Audit Committee
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Compensation Committee
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Nominating and Governance Committee
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Ray Aspiri |
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Thomas J. Cable |
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Peter A. Demopulos, M.D. |
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Gregory A. Demopulos, M.D. |
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Arnold C. Hanish |
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Leroy E. Hood, M.D., Ph.D. |
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Rajiv Shah, M.D. |
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Corporate Governance Documents
Please visit our investor relations website at investor.omeros.com, under “Governance,” for additional information on our corporate governance including:
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the charters approved by our board of directors for the audit committee, compensation committee and nominating and governance committee; |
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the code of business conduct and ethics; |
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the corporate governance principles, which includes policies on shareholder communications with the board of directors, director attendance at our annual meetings and succession planning; and |
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the lead independent director charter. |
In the event of any amendment to, or waiver from, a provision of our code of business conduct and ethics, we will promptly post on our investor relations website relevant information regarding the amendment or waiver, including the date and the nature of the event.
Whistleblower Policy
We have adopted a whistleblower policy applicable to our employees that provides for protection from retaliation or discrimination by our company due to reporting issues relating to compliance with applicable laws and regulations.
Audit Committee
Membership and Independence
The members of our audit committee are Mr. Aspiri, Mr. Cable and Mr. Hanish. Mr. Hanish is the chairman of our audit committee. Our board of directors has determined that each member of our audit committee meets current Nasdaq requirements for independence for audit committee members. Our board of directors has also determined that Mr. Hanish is an “audit committee financial expert” as defined in SEC rules. Our audit committee held a total of eight meetings and acted by unanimous written consent one time during 2015.
Responsibilities
Under its charter, the audit committee is responsible for, among other things:
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selecting and hiring our independent auditors, and approving the audit and non-audit services to be performed by our independent registered public accounting firm; |
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evaluating the qualifications, performance and independence of our independent registered public accounting firm; |
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|
· |
monitoring the integrity of our financial statements and our compliance with legal and regulatory requirements as they relate to financial statements or accounting matters; |
|
· |
reviewing with our independent registered public accounting firm and management significant issues that arise regarding accounting principles and financial statement presentation, and matters concerning the scope, adequacy and effectiveness of our financial controls; |
|
· |
reviewing the adequacy and effectiveness of our internal control policies and procedures; |
|
· |
establishing procedures for the receipt, retention and treatment of complaints received by us regarding accounting, internal accounting controls or auditing matters; |
|
· |
reviewing and approving in advance any proposed related-party transactions and monitoring compliance with our code of business conduct and ethics; and |
|
· |
preparing the audit committee report that the SEC requires in our annual meeting proxy statements. |
Compensation Committee
Membership and Independence
The members of our compensation committee are Mr. Aspiri, Mr. Cable and Dr. Hood. Mr. Aspiri is the chairman of our compensation committee. Our board of directors has determined that each member of our compensation committee meets current Nasdaq requirements for independence of compensation committee members. In addition, our board of directors has determined that each member of the compensation committee is a non-employee director for purposes of Rule 16b-3 of the Exchange Act. Our compensation committee held a total of six meetings and acted by unanimous written consent one time during 2015.
Responsibilities
Under its charter, the compensation committee is responsible for, among other things:
|
· |
evaluating the performance of our executive officers and approving their compensation and other terms of employment and reviewing and approving corporate performance goals and objectives relevant to such compensation; |
|
· |
evaluating and recommending to our board of directors the type and amount of compensation to be paid or awarded to board members; |
|
· |
evaluating and recommending to our board of directors the equity incentive plans, compensation plans and similar programs advisable for us; |
|
· |
administering our equity incentive plans; |
|
· |
reviewing and approving the terms of any employment agreements, severance arrangements, change in control protections and any other compensatory arrangements for our executive officers; and |
|
· |
preparing the compensation committee report that the SEC requires in our annual proxy statement. |
Processes and Procedures
Our board of directors has delegated to the compensation committee the authority to determine the compensation for our executive officers. Non-executive director compensation is recommended by our compensation committee to the board of directors for approval. Our executive officers participate in general discussions with our compensation committee and board of directors about these compensation matters but they do not participate in discussions during which their individual compensation is being considered and approved. The compensation committee may delegate any or all of its authority under its charter to one or more subcommittees. The compensation committee may also delegate to our CEO the authority to grant employee stock options or other equity-based awards to employees of the company or any subsidiary of the company who are not directors or executive officers of the company, on such terms and subject to such limitations as the compensation committee may determine.
Compensation Committee Interlocks and Insider Participation
During 2015, Mr. Aspiri, Mr. Cable and Dr. Hood served on our compensation committee. During 2015, no member of our compensation committee was an officer or employee or formerly an officer of our company, and, except as set forth under the section entitled “Transactions with Related Persons” in this proxy statement, no member had any relationship that would require disclosure as a related person transaction under Item 404 of Regulation S-K. None of our executive officers currently serves, or in the past year has
8
served, as a member of the board of directors or compensation committee of any entity that has one or more executive officers serving on our board of directors or compensation committee.
Nominating and Governance Committee
Membership and Independence
The members of our nominating and governance committee are Mr. Cable, Mr. Aspiri and Dr. Hood. Mr. Cable is the chairman of our nominating and governance committee. Our board of directors has determined that each member of our nominating and governance committee meets current Nasdaq requirements for independence. Our nominating and governance committee held two meetings in 2015.
Responsibilities
Under its charter, the nominating and governance committee is responsible for, among other things:
|
· |
assisting the board in identifying prospective director nominees and recommending director nominees to our board for each annual meeting of shareholders; |
|
· |
evaluating nominations by shareholders of candidates for election to our board; |
|
· |
recommending governance principles to our board; |
|
· |
overseeing the evaluation of our board of directors; |
|
· |
reviewing shareholder proposals for our annual meetings; |
|
· |
evaluating proposed changes to our charter documents; |
|
· |
reviewing and assessing our senior management succession plan; and |
|
· |
recommending to our board the members for each board committee. |
Shareholder Recommendations and Nominees
It is the policy of our board of directors that the nominating and governance committee consider both recommendations and nominations for candidates to the board from shareholders so long as such recommendations and nominations comply with our articles of incorporation, bylaws and applicable law, including the rules and regulations of the SEC. Shareholders may recommend director nominees for consideration by the nominating and governance committee by writing to us at the address below and providing evidence of the shareholder’s ownership of our stock, the nominee’s name, home and business address and other contact information, as well as the nominee’s detailed biographical data and qualifications for board membership, and information regarding any relationships between the recommended candidate and us within the last three fiscal years.
Following verification of the shareholder status of the person submitting the recommendation, all properly submitted recommendations will be promptly brought to the attention of the nominating and governance committee. Shareholders who desire to nominate persons directly for election to the board at an annual meeting of shareholders must meet the deadlines and other requirements set forth in our bylaws and the rules and regulations of the SEC. See “Shareholder Proposals for 2017 Annual Meeting.” Any vacancies on the board occurring between our annual meetings of shareholders may be filled by persons selected by a majority of the directors then in office, and any director so elected will serve until the next shareholders’ meeting at which directors are elected.
You may write to the nominating and governance committee at:
Omeros Corporation
The Omeros Building
201 Elliott Avenue West
Seattle, WA 98119
Attn: Nominating and Governance Committee
c/o Office of the General Counsel
9
The nominating and governance committee works with our chief executive officer to identify and recruit new directors and considers candidates proposed by shareholders as part of this process. The committee may also engage consultants or search firms, as it deems advisable, to identify director candidates. Our board of directors believes that there are no specific minimum qualifications that must be met by each candidate for the board, nor are there specific qualities or skills that are necessary for one or more of the members of the board to possess, except as may be required by rules promulgated by Nasdaq or the SEC. In evaluating the qualifications of the candidates, the nominating and governance committee will consider many factors, including issues of character, judgment, independence, diversity, age, expertise, diversity of experience, length of service and other commitments. The nominating and governance committee will evaluate such factors, among others, and does not assign any particular weighting or priority to any of these factors. The committee will consider each individual candidate in the context of the current perceived needs of the board as a whole. Although the committee may choose to consider diversity as one factor in evaluating candidates, we do not have a policy that requires the committee to consider diversity. While the board of directors has not established specific minimum qualifications for director candidates, the board believes that candidates and nominees must reflect a board that is comprised of directors who (a) are predominantly independent, (b) are of high integrity, (c) have qualifications that will increase overall board effectiveness and (d) meet other requirements as may be required by applicable rules of Nasdaq and the SEC.
Shareholder Communication with the Board of Directors
It is the policy of our board of directors to allow shareholders to communicate with its members. Communications may be addressed to the entire board, to the non-management directors as a group or to any individual director. All such communications will be initially received and processed by the office of our general counsel. Spam, junk mail, product complaints, product inquiries, new product suggestions, resumes and other forms of job inquiries, surveys, business solicitations and advertisements and threatening, hostile, illegal and similar unsuitable communications will not be delivered to the board, but will be made available to a director upon request. To contact members of the board of directors, a shareholder should send a letter to the following address:
Omeros Corporation
The Omeros Building
201 Elliott Avenue West
Seattle, WA 98119
Attn: The Board of Directors
c/o Office of the General Counsel
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NON-EMPLOYEE DIRECTOR COMPENSATION
In 2015, our non-employee directors received cash compensation for their services in the following amounts: $20,000 for service on the board of directors; $1,750 for each meeting of the board of directors attended in person; $500 for each meeting of the board of directors attended by telephone; and $500 for each committee meeting attended in person or by telephone. In addition, we pay the chairs of our audit, compensation and nominating and governance committees $15,000, $10,000 and $5,000 per year, respectively, for their service. Director fees are paid on a quarterly basis as earned.
Each individual who is first elected or appointed as a non-employee member of the board of directors is automatically granted an option to purchase 15,000 shares of our common stock that vests in equal annual installments over a three-year period beginning on the date the director takes office. In addition, on the date of each annual meeting of shareholders, each non-employee director who has served as a director for at least six months and who will continue to serve as a director after the annual meeting is automatically granted an option to purchase 5,000 shares of our common stock that will vest in full on the day prior to the date of the next annual meeting of shareholders. The per share exercise price for options granted to non-employee directors is equal to the closing public trading price of our common stock on the date of grant, and vesting is conditioned upon the director’s continued service as a director through the applicable vesting dates.
2015 Non-Employee Director Compensation
The following table shows the compensation of each of our non-employee directors during the fiscal year ended December 31, 2015:
Name |
|
Fees Earned or Paid in Cash ($) |
|
|
Option Awards ($)(1)(2) |
|
|
Total ($) |
|
|||
Ray Aspiri |
|
|
46,000 |
|
|
|
64,022 |
|
|
|
110,022 |
|
Thomas J. Cable |
|
|
41,000 |
|
|
|
64,022 |
|
|
|
105,022 |
|
Peter A. Demopulos, M.D. |
|
|
28,000 |
|
|
|
64,022 |
|
|
|
92,022 |
|
Arnold C. Hanish |
|
|
46,250 |
|
|
|
64,022 |
|
|
|
110,272 |
|
Leroy E. Hood, M.D., Ph.D. |
|
|
29,000 |
|
|
|
64,022 |
|
|
|
93,022 |
|
Rajiv Shah, M.D. (3) |
|
|
13,639 |
|
|
|
184,566 |
|
|
|
198,205 |
|
(1) |
The amounts reported in this column represent the grant date fair value of option awards granted to our non-employee directors during 2015 as computed in accordance with FASB ASC Topic 718. The assumptions used to calculate the value of these option awards are set forth in Note 11 to our consolidated financial statements included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2015. |
(2) |
As of December 31, 2015, Mr. Aspiri, Mr. Cable, Dr. Peter Demopulos, Mr. Hanish, Dr. Hood and Dr. Shah held options to purchase 15,000, 40,000, 28,334, 30,000, 40,000 and 15,000 shares of our common stock, respectively. |
(3) |
Dr. Shah was appointed to our board of directors on June 14, 2015. Pursuant to our non-employee director compensation policy, Dr. Shah was granted a stock option to purchase 15,000 shares of our common stock on the date of his appointment. |
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Compensation Discussion and Analysis
This Compensation Discussion and Analysis provides an overview of our executive compensation philosophy, the overall objectives of our executive compensation program and the components of our compensation program for our named executive officers. This section also discusses our executive compensation process. When we refer to our named executive officers in this proxy statement, we are referring to the following individuals, who are our only executive officers:
|
· |
Gregory A. Demopulos, M.D., our president, chief executive officer and chairman of the board of directors, who is referred to as our CEO; |
|
· |
Michael A. Jacobsen, our vice president, finance, chief accounting officer and treasurer, who is referred to as our PFO; and |
|
· |
Marcia S. Kelbon, J.D., M.S., our vice president, patent and general counsel and secretary. |
This Compensation Discussion and Analysis contains forward-looking statements that are based on our current plans, considerations, expectations, and determinations regarding future compensation programs. The actual compensation programs that we adopt may differ materially from currently planned programs as summarized in this discussion.
Executive Summary
Business Highlights
During 2015, we launched our first commercial drug product OMIDRIA® (phenylephrine and ketorolac injection) 1%/0.3% in the U.S., completing our transition into a commercial enterprise, and achieved several successes in development of our product pipeline. These advances included the items listed below.
|
· |
We broadly launched OMIDRIA in the U.S. in April 2015 by selling primarily through wholesalers that, in turn, sell to ambulatory surgery centers, or ASCs. OMIDIRA is approved by the U.S. Food and Drug Administration, or FDA, for use during cataract surgery or intraocular lens replacement to maintain pupil size by preventing intraoperative miosis (pupil constriction) and to reduce postoperative ocular pain. The broad U.S. launch followed a successful controlled launch of OMIDIRA to a small number of ASCs in the U.S. in February 2015. We recorded net OMIDRIA product sales for the year ended December 31, 2015 of $13.3 million. |
|
· |
We confirmed coverage for OMIDIRA with nearly all of the 30 largest commercial third-party payers in the U.S., as well as a large number of regional commercial payers. We also entered into agreements to enable discounts that do not affect average selling price, or ASP, on qualifying purchases of OMIDIRA by certain U.S. government purchasers and other eligible entities (e.g., 340B-eligible hospitals and clinics). In addition, to ensure availability of OMIDRIA to all U.S. cataract surgery patients, in October 2015 we launched the OMIDRIAssure™ Reimbursement Services Program, providing reimbursement support services, free product based on the financial need of government-insured or uninsured patients and financial assistance for patients whose commercial insurance is inadequate to cover fully the cost of OMIDIRA. |
|
· |
The European Commission granted marketing authorization for OMIDIRA in the European Union, or EU, for use in cataract surgery and lens replacement procedures to maintain mydriasis (pupil dilation), to prevent miosis (pupil constriction) and to reduce postoperative eye pain. The approval allows for the marketing of OMIDIRA in all EU member states plus Iceland, Lichtenstein, and Norway. |
|
· |
We completed the dose-ranging stage of our Phase 2 clinical trial of OMS721, the lead human monoclonal antibody for our mannan-binding lectin-associated serine protease-2, or MASP-2, program, in patients with complement-mediated thrombotic microangiopathies, including atypical hemolytic uremic syndrome, or aHUS, and commenced the fixed-dose stage of the clinical trial. Results from the Phase 2 trial were used to support our request to the FDA to progress OMS721 to a Phase 3 program in patients with aHUS. In addition, the FDA granted Fast Track designation to OMS721 for the treatment of for the treatment of patients with aHUS. |
|
· |
Based on FDA’s review of our submission of requested data and subsequent discussions with the FDA, we re-initiated our OMS824 Phase 2 program in patients with Huntington’s disease with a dosing limitation. The dosing limitation is subject to removal pending submission and FDA review of additional information, and we are conducting additional nonclinical studies aimed at removing that limitation. In addition, we currently are designing a new Phase 2 clinical trial and have reason to believe it should demonstrate a beneficial effect of OMS824 in Huntington’s. |
12
Significant Executive Compensation Actions
We determine compensation for our named executive officers based on their ability to achieve operational goals that further our long-term business objectives and create sustainable long-term shareholder value in a cost-effective manner. In 2015, our compensation committee did not approve any salary adjustments, bonuses or equity awards to our named executive officers. The principal reasons that we elected not to approve salary adjustments or bonuses in 2015 were our desire to preserve capital in order to focus our efforts toward the U.S. launch of OMIDRIA as well as the desire to continue investment in our clinical and preclinical programs. In February 2016, the compensation committee, in connection with the approval of stock option awards to all employees, reviewed our executive compensation program and approved stock option awards to our named executive officers that were intended to be our annual stock option awards relating to 2014 company and individual performance. Our compensation committee is also evaluating potential salary increases and bonuses for our executive employees (i.e., vice president level and above), including our named executive officers. These decisions are expected to take into account the fact that we have not adjusted executive salaries since 2014 and have not paid bonuses to executives since 2012. We expect to pay bonuses to our executive employees, including the named executive officers, in 2016 in cash and/or equity based on company and individual performance in 2015 and prior years, among other factors.
Response to “Say-on-Pay” Votes at our 2014 Annual Meeting of Shareholders
At our 2014 Annual Meeting of Shareholders, we conducted a non-binding advisory shareholder vote (a so-called “say-on-pay” vote) on the compensation of our named executive officers. At that meeting, 96% of the votes cast were voted in favor of our executive compensation policies and practices, as disclosed in the proxy statement for the meeting. Our compensation committee is mindful of the support our shareholders have expressed for our compensation policies and practices when evaluating our executive compensation program, policies and practices. As a result, our compensation committee decided to retain our general approach to executive compensation during its 2015 review of our executive compensation philosophy.
At the 2011 Annual Meeting of Shareholders, our shareholders voted on an advisory resolution to express their preference as to whether we should hold future say-on-pay votes every one, two or three years. Consistent with the board of directors’ recommendation, 68% of the votes cast were in favor of a frequency of once every three years. In light of this result, the board of directors determined that we will hold say-on-pay votes every three years until the next non-binding advisory vote on the frequency of future say-on-pay votes occurs. We will conduct our next say-on-pay vote and vote on the frequency of future say-on-pay votes at our 2017 Annual Meeting of Shareholders.
Executive Compensation Philosophy and Objectives
We operate in a highly competitive business environment, which is constantly reshaped by medical advances, frequent changes to market and regulatory requirements and the emergence of new competitive technologies. To thrive in this environment, we must work rapidly to create and refine new development programs and product candidates, drive product candidates toward commercialization, achieve commercial objectives and demonstrate an ability to quickly identify and capitalize on new business opportunities. To achieve these goals, we need a highly talented team of technical and business professionals.
We compete with many other companies in seeking to attract and retain a skilled management team. To meet this challenge, we have employed a compensation philosophy of offering our executive officers competitive compensation and benefits packages that are focused on long-term shareholder value creation and rewarding our executive officers for achieving our strategic objectives.
We orient our executive compensation program to:
|
· |
provide total compensation opportunities that enable us to recruit and retain executives with the experience and skills to manage the growth of our company and lead us to the next stage of development; |
|
· |
establish a clear alignment between the interests of our executives and the interests of our shareholders; |
|
· |
reinforce a culture of ownership, excellence and urgency; and |
|
· |
create a direct and meaningful link between company business results, individual performance and compensation. |
13
Executive Compensation-Setting Process
Role of the Compensation Committee
The compensation committee of our board of directors is responsible for establishing our executive compensation philosophy and administering our executive compensation program, as well as determining and approving the compensation for our executive officers. The compensation committee periodically reports to our board of directors on its deliberations and actions. The compensation committee, with the assistance of Compensia, a national compensation consulting firm providing executive compensation advisory services, reviews our executive compensation program, including any incentive compensation plans, to determine whether they are appropriate, properly coordinated and achieve their intended purposes. Our compensation committee completed this review of our compensation program in December 2015 and performed a subsequent review in connection with its decision to grant equity awards in February 2016. In addition to the services mentioned above, Compensia also recommends to our board of directors any modifications of our existing plans, or new plans or programs, from time to time as requested by our board of directors or compensation committee.
Role of Management
In carrying out its responsibilities, the compensation committee works with members of our management, including our CEO. Typically, our senior management assists the compensation committee and Compensia by providing information on company and individual performance, market data and management’s perspective and recommendations on compensation matters. Our CEO, using competitive market data compiled by Compensia and after discussion with Compensia, makes recommendations to the compensation committee regarding the compensation of our executive officers and significant employees, including Ms. Kelbon and Mr. Jacobsen, and attends compensation committee meetings. Our CEO does not make recommendations with respect to his own compensation and excuses himself from compensation committee meetings when his compensation is discussed.
While the compensation committee solicits and reviews our CEO’s recommendations and proposals with respect to compensation-related matters and receives guidance from Compensia, the compensation committee makes its decisions independently and may consider factors and information other than our CEO’s recommendations and proposals.
Role of Compensation Consultant
The compensation committee is authorized to retain the services of compensation consultants and other advisors from time to time, as it sees fit, in connection with the establishment of cash and equity compensation plans and arrangements and related policies. The compensation committee has engaged Compensia to assist it in developing a set of executive compensation guiding principles, to evaluate the competitiveness of our executive officers’ compensation and to assist the compensation committee in designing and implementing our executive compensation program. Compensia serves at the discretion of the compensation committee. Our compensation committee has evaluated Compensia’s independence using factors specified by the SEC and Nasdaq listing standards and has determined that the work performed by Compensia in 2015 does not give rise to any conflict of interest. Compensia provided executive and board cash and equity compensation advisory services to us in 2015 but did not provide other services.
Use of Competitive Data
To assess the competitiveness of our executive compensation program and current compensation levels and to assist it in setting compensation levels, the compensation committee refers to compensation data compiled with respect to the compensation paid to executives in a peer group of comparable companies in our industry. Compensia developed this group, which we refer to as the Peer Group, with our input in 2014. Companies were selected for the Peer Group based on their similarities to Omeros, including their stage of development, number of development programs, revenue and market capitalization, as well as our expectations regarding commercialization of OMIDRIA. Compensation data for the companies comprising the Peer Group is gathered from public filings and supplemented by survey data from the Radford Global Life Sciences Survey. The Peer Group is comprised of the following companies:
Aegerion Pharmaceuticals, Inc. |
Anika Therapeutics, Inc. |
Arena Pharmaceuticals, Inc. |
Avanir Pharmaceuticals, Inc. |
Dendreon Corporation |
Dyax Corp. |
Exelixis, Inc. |
Hyperion Therapeutics, Inc. |
Insys Therapeutics, Inc. |
MannKind Corporation |
Momenta Pharmaceuticals, Inc. |
NPS Pharmaceuticals, Inc. |
Pacira Pharmaceuticals, Inc. |
Spectrum Pharmaceuticals, Inc. |
Sucampo Pharmaceuticals, Inc. |
Vanda Pharmaceuticals Inc. |
14
The compensation committee reviewed this Peer Group data when making its decisions about stock option awards in February 2016.
Compensation Program Design
In 2015, compensation of our named executive officers consisted solely of base salary and certain employee benefits and perquisites. However, compensation for our named executive officers in other years typically includes annual stock option awards and, in some years, has also included bonuses. In most years, we expect that the compensation of our named executive officers will include one or more of these additional compensation items and, to this end, our compensation committee granted equity awards in February 2016. We expect to make annual equity award grants to employees, including our named executive officers, in 2016 based in part on company and individual performance in 2015. We also expect to pay bonuses to and approve base salary adjustments for certain employees at the vice president level and above, including the named executive officers, in 2016 on the basis of company and individual performance in 2015 and prior years, among other factors.
We do not specifically allocate between short- and long-term compensation and equity and cash compensation. The compensation committee considers each compensation element separately and then reviews the total compensation to consider whether it is appropriate in light of our performance, our named executive officers’ individual performance and our liquidity requirements. The compensation committee also gives weight in making compensation decisions to relative internal pay equity among our named executive officers and significant employees as well as among our employees generally, commensurate with their relative contributions. The compensation committee periodically reviews our executive compensation program to assess whether it creates an inappropriate or excessive risk that is likely to have a material adverse effect on us.
Executive Compensation Program Components
The following is a description of each component of our executive compensation program, the rationale for each component and how awards are determined.
Base Salary
Base salaries are used to recognize the experience, skills, knowledge and responsibilities required of our named executive officers. The compensation committee reviews the base salaries of our named executive officers each year. In assessing these base salary levels, the compensation committee considers market competitiveness based on Peer Group and survey data, the executive officer’s past and expected future contribution to Omeros, his or her knowledge, experience and responsibilities and the relative base salaries and responsibilities of the other members of our management team.
The compensation committee did not adjust the base salaries of our executive officers in 2015, as stated above, but retains the discretion to, and may, increase salaries for our executive officers in connection with the review of their performance in 2013, 2014 and 2015, as applicable. Base salaries for our named executive officers as of December 31, 2015 were as follows:
Named Executive Officer |
|
2015 Base Salary |
|
|
Gregory A. Demopulos, M.D. |
|
$ |
669,500 |
|
Michael A. Jacobsen |
|
$ |
285,000 |
|
Marcia S. Kelbon, J.D., M.S. |
|
$ |
345,050 |
|
Bonuses
From time to time we may pay discretionary bonuses to reward, incentivize and retain employees, including our named executive officers. If we elect to pay such bonuses, we expect to consider prior company and individual performance, current and anticipated business objectives, Peer Group data, relative internal pay equity and other factors.
As noted above, the compensation committee elected not to pay bonuses to our named executive officers in 2015. We have not paid bonuses to our employees at the vice president level and above, including our named executive officers, since 2012. If the compensation committee determines to pay bonuses to our named executive officers, which is expected in 2016, it may pay such bonuses in cash and/or equity and take into consideration individual and company performance in 2015 and prior years, among other factors.
15
We use equity awards to provide incentives and to reward our named executive officers for long-term corporate performance based on the value of our common stock and, thereby, align the interests of our executive officers with those of our shareholders. Historically, we have not applied a rigid formula in determining the size of the equity awards that were granted to our executive officers. Instead, the compensation committee has exercised its judgment, taking into consideration, among other things, Peer Group data compiled by, and the counsel of, Compensia as well as company performance, an evaluation of the expected and actual performance of each named executive officer, each named executive officer’s responsibilities, experience, skills and contributions, the cash compensation received by each named executive officer, relative internal pay equity and market conditions. The compensation committee generally also considers the existing equity holdings of each named executive officer, including the current economic value of their unvested equity and the ability of these unvested holdings to satisfy our objectives of retaining and incentivizing our executive officers. Based on these factors, the compensation committee, with guidance from Compensia, determines the size of each award at levels it considered appropriate to create a meaningful opportunity for reward predicated on the creation of long-term shareholder value. The compensation committee has historically granted equity awards in the form of stock options, although it is authorized to grant other types of equity awards, including restricted stock and restricted stock units, and may do so in the future.
The compensation committee usually grants stock option awards annually, although it did not make grants to our executive officers or other employees, other than new hire grants, during 2015. In February 2016, the compensation committee granted stock option awards to our employees, including our named executive officers, that were intended to be our annual stock option awards relating to 2014. In determining the size of the stock option awards for the named executive officers, the compensation committee considered the factors described above.
Although the compensation committee does not maintain a fixed date for making compensation determinations, our compensation program changes historically have been made effective in April of each year. Accordingly, the vesting commencement dates of stock options granted in connection with the review of prior performance typically begin in April of the year following the applicable performance year. These stock option awards vest in equal monthly installments over a four-year period beginning on the vesting commencement date. The per share exercise price for our stock option awards is equal to the fair market value of our common stock on the date of grant. The fair market value is the closing public trading price of our common stock on the date of grant or, if the equity award is granted on a day when the trading market for our common stock is closed, the closing public trading price on the most recent trading day.
The February 2016 stock option awards for our named executive officers were as follows:
|
|
Number of Shares of Common |
|
|
|
|
Stock Underlying Stock Option Awards |
|
|
Named Executive Officer |
|
Granted February 2016(1) |
|
|
Gregory A. Demopulos, M.D. |
|
|
400,000 |
|
Michael A. Jacobsen |
|
|
85,000 |
|
Marcia S. Kelbon, J.D., M.S. |
|
|
80,000 |
|
(1) |
These stock option awards have a per share exercise price of $10.27. |
Consistent with our historical practice, the vesting commencement dates of the stock option awards granted in February 2016 were made retroactive to April 2015 and vest in equal monthly installments over a four-year period beginning on the vesting commencement date. These stock option awards will be described in more detail in the proxy statement for the 2017 Annual Meeting and disclosed in the summary compensation table in that proxy statement.
Retirement and Other Benefits
We have established a broad-based tax-qualified Section 401(k) retirement savings plan for our employees, including our named executive officers, who satisfy certain eligibility requirements. Under this plan, participants may elect to make pre-tax contributions, or post-tax contributions under a Roth option, of up to 100% of their current compensation, not to exceed the applicable statutory income tax limitation (which was $18,000 in 2015, or $24,000 if over age 50). We do not currently match contributions made by participants in the plan. We intend for the plan to qualify under Section 401(a) of the Internal Revenue Code, or the Code, so that deferral contributions by participants to the plan, and income earned on plan contributions, are not taxable to participants until withdrawn from the plan.
Additional benefits received by our employees, including our named executive officers, include medical, dental and vision benefits, medical and dependent care flexible spending accounts, short- and long-term disability insurance, accidental death and dismemberment insurance and basic life insurance coverage. These benefits are provided to our named executive officers on the same basis as to all of our full-time employees.
16
We design our employee benefits programs to be affordable and competitive in relation to the market as well as compliant with applicable laws and practices. We adjust our employee benefits programs as needed based upon regular monitoring of applicable laws and practices and the competitive market.
Perquisites and Other Personal Benefits
Historically, with the exception of parking expenses, we only have provided perquisites or other personal benefits to our CEO. Pursuant to the terms of his employment agreement, we paid certain expenses incurred by our CEO, including his medical malpractice insurance premiums and practice fees so that he may continue to practice medicine as well as parking expenses and business-related information technology expenses. We believe that his ability to maintain his position as a practicing surgeon is beneficial to our corporate objectives including, for example, by providing him with insight in determining the strategic direction of the company and our specific drug development programs as well as establishing relationships with key medical opinion leaders.
Currently, we do not view perquisites or other personal benefits as a significant component of our executive compensation program. In the future, however, we may provide such items in limited circumstances, such as when we believe it is appropriate to assist an individual in the performance of his or her duties, to make our executives more efficient and effective and for recruitment, motivation or retention purposes. All future practices with respect to significant perquisites or other personal benefits will be approved and subject to periodic review by the compensation committee. Our named executive officers are not eligible to receive any tax “gross-ups” or other tax reimbursement payments.
Employment Agreement and Post-Employment Compensation
Except for our CEO, we do not have formal employment agreements with our named executive officers. For a summary of the material terms and conditions of the employment agreement with our CEO, see “Employment Agreement with Gregory A. Demopulos, M.D.” below in this proxy statement. Our CEO’s current employment agreement, which was entered into in 2010, was deemed necessary by our compensation committee to provide a competitive compensation package to retain someone with his unique skill set and medical expertise. At the same time, the compensation committee was sensitive to the need to balance the market competitiveness with the financial limitations of a development-stage life sciences company. As part of his pay package, the CEO’s employment agreement includes certain protections in the event of his termination of employment under specified circumstances, including following a change in control of our company. The compensation committee determined that these protections were necessary to induce our CEO to limit his medical practice in exchange for the uncertainty of a demanding position in the company. The compensation committee believes that these protections continue to serve a retention purpose and help our CEO maintain his focus on his duty to maximize shareholder value if there is a potential transaction that could involve a change in control of our company. The terms of his agreement were determined by the compensation committee based on negotiations with our CEO. For a summary of the material terms and conditions of these provisions, see “Potential Payments upon Termination or Change in Control” below in this proxy statement.
In addition, we provide all of our employees, including our named executive officers, with certain change in control vesting benefits for their equity compensation. We have provided this benefit to encourage our employees to focus on their responsibilities and not be distracted by the potential effect of a change in control on their employment situation. For a summary of the material terms and conditions of these benefits, see “Potential Payments upon Termination or Change in Control” below in this proxy statement.
Hedging and Pledging Policy
Under our insider trading policy, all of our employees, including our executive officers, as well as our directors are prohibited from engaging in short sales of our stock as well as in transactions in publicly traded options, such as puts and calls, or in other derivative securities of our common stock, with the exception of securities issued pursuant to our compensatory benefit plans. This prohibition extends to any hedging or similar transaction designed to decrease the risks associated with holding our securities. Our insider trading policy also prohibits our executive officers and directors from pledging our securities as collateral for loans or holding our securities in margin accounts in which the securities may be sold without the officer’s or director’s consent unless certain preclearance requirements and restrictions are satisfied including approval by our board of directors or the audit committee of the board of directors. As permitted by our insider trading policy, exemptions were granted with respect to our CEO and The Demopulos Family Trust in 2015 and to Peter A. Demopulos in 2016 to permit each to pledge shares of Omeros common stock as collateral for a line of credit for each such shareholder. These exemptions were granted after each shareholder demonstrated, to the reasonable satisfaction of the board of directors or audit committee (as applicable), that the shareholder had adequate resources, excluding Omeros stock, to repay the loan in full and thereby had the capacity to avoid an involuntary sale of the shareholder’s Omeros stock by the respective lender.
17
Tax and Accounting Considerations
Deductibility of Executive Compensation
Generally, Section 162(m) of the Code disallows a tax deduction to any publicly held corporation for any remuneration in excess of $1.0 million paid in any taxable year to its chief executive officer and each of its other three most highly-compensated executive officers (other than its principal financial officer). In certain circumstances, remuneration in excess of $1.0 million may be deducted if it (i) qualifies as “performance-based compensation” within the meaning of the Code or (ii) is paid under a plan that existed before a company completes its initial public offering if the awards under the plan are granted within a specified period following the initial public offering. At present, awards granted after May 24, 2013 under the 2008 Plan do not qualify for either exemption because the exemption following completion of our initial public offering expired after the 2013 Annual Meeting of Shareholders. As described above, the compensation committee believes that its primary responsibility is to provide a compensation program that attracts, retains and rewards executive officers necessary for the company’s success. Accordingly, while the compensation committee considers all elements of the cost to us of providing compensation in approving the amount and form of compensation for our executives, the compensation committee may, in its judgment, authorize compensation payments that do not comply with an exemption from the 162(m) deductibility limit when it believes that such payments are appropriate to attract, retain and reward executive talent and to promote our corporate objectives.
Taxation of “Parachute” Payments and Deferred Compensation
Sections 280G and 4999 of the Code provide that executive officers and directors who hold significant equity interests and certain other service providers may be subject to an excise tax if they receive payments or benefits in connection with a change in control of our company that exceeds certain prescribed limits, and that our company (or a successor) may forfeit a deduction on the amounts subject to this additional tax. We are not obligated to provide any named executive officer with a “gross-up” or other reimbursement payment for any tax liability that may become payable as a result of the application of Sections 280G or 4999.
Section 409A of the Code imposes significant additional taxes if an executive officer, director or service provider receives “deferred compensation” that does not satisfy the restrictive conditions of the provision. Although we did not have a traditional nonqualified deferred compensation plan in place for executives during 2015, Section 409A applies to certain equity awards and severance arrangements. We believe that we have structured equity awards in a manner intended to comply with the applicable Section 409A conditions.
Accounting for Stock-Based Compensation
We follow FASB ASC Topic 718, Compensation — Stock Compensation, for our stock-based compensation awards. FASB ASC 718 requires companies to calculate the grant date “fair value” of their stock-based awards using a variety of assumptions. This calculation is performed for accounting purposes and reported in the compensation tables below, even though recipients may never realize any value from their awards. FASB ASC 718 also requires companies to recognize the compensation cost of their stock-based awards in their income statements over the period that an employee is required to render service in exchange for the award.
Compensation Committee Report
The compensation committee has reviewed and discussed the Compensation Discussion and Analysis contained in this proxy statement with management and, based on such review and discussion, has recommended to the board of directors that the Compensation Discussion and Analysis be included in this proxy statement and incorporated by reference into our Annual Report on Form 10-K for the year ended December 31, 2015.
COMPENSATION COMMITTEE
Ray Aspiri, Chairman
Thomas J. Cable
Leroy E. Hood, M.D., Ph.D.
18
The following table reflects our named executive officers’ compensation for the years ended December 31, 2015, 2014 and 2013.
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|
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|
|
|
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|
|
|
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Non-Equity |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Option |
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|
Incentive Plan |
|
|
All Other |
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|
|
|
|||
|
|
|
|
Salary |
|
|
Bonus |
|
|
Awards |
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|
Compensation |
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|
Compensation |
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Total |
|
||||||
Name and Principal Position |
|
Year |
|
($)(1) |
|
|
($) |
|
|
($)(2) |
|
|
($) |
|
|
($)(3) |
|
|
($) |
|
||||||
Gregory A. Demopulos, M.D. |
|
2015 |
|
|
669,500 |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
14,092 |
|
|
|
683,592 |
|
President, Chief Executive Officer and |
|
2014 |
|
|
684,125 |
|
|
|
— |
|
|
|
3,236,715 |
|
|
|
— |
|
|
|
17,195 |
|
|
|
3,938,035 |
|
Chairman of the Board of Directors |
|
2013 |
|
|
650,000 |
|
|
|
— |
|
|
|
2,571,478 |
|
|
|
— |
|
|
|
14,881 |
|
|
|
3,236,359 |
|
Michael A. Jacobsen |
|
2015 |
|
|
285,000 |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
2,545 |
|
|
|
287,545 |
|
Vice President, Finance, Chief Accounting |
|
2014 |
|
|
285,000 |
|
|
|
— |
|
|
|
719,720 |
|
|
|
— |
|
|
|
2,398 |
|
|
|
1,007,118 |
|
Officer and Treasurer |
|
2013 |
|
|
79,745 |
|
|
|
— |
|
|
|
706,771 |
|
|
|
— |
|
|
|
717 |
|
|
|
787,233 |
|
Marcia S. Kelbon, J.D., M.S. |
|
2015 |
|
|
345,050 |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
2,640 |
|
|
|
347,690 |
|
Vice President, Patent and General |
|
2014 |
|
|
352,587 |
|
|
|
— |
|
|
|
791,197 |
|
|
|
— |
|
|
|
2,456 |
|
|
|
1,146,240 |
|
Counsel and Secretary |
|
2013 |
|
|
335,000 |
|
|
|
— |
|
|
|
700,436 |
|
|
|
— |
|
|
|
2,169 |
|
|
|
1,037,605 |
|
(1) |
The 2014 salary amounts include lump sum payments for each of our named executive officers made in 2014 for salary adjustments that were made in 2014 and applied retroactively to April 2013. |
(2) |
Amounts shown in this column do not reflect compensation realized by the named executive officers. Instead, the dollar amounts reported in this column represent the grant date fair value of option awards granted to our named executive officers during the applicable year as computed in accordance with FASB ASC Topic 718. The assumptions used to calculate the value of option awards are set forth in Note 11 to our consolidated financial statements included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2015. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeiture related to service-based vesting conditions. Realization of the compensation reported in this column, if any, is dependent upon the price of our common stock at the time the stock options are exercised. |
(3) |
All Other Compensation includes perquisites and other personal benefits paid to Dr. Demopulos of $13,312, $16,694 and $14,812 in 2015, 2014 and 2013, respectively. Perquisites and personal benefits provided in 2015 consisted of expenses incurred by Dr. Demopulos to retain his medical license, including medical malpractice insurance premiums and practice fees, parking expenses, business-related information technology expenses and a portion of his business-related travel expenses. |
19
Outstanding Equity Awards at 2015 Fiscal Year-End
The following table reflects outstanding equity awards held by each of the named executive officers as of December 31, 2015.
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Number of |
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|
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Number of |
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|
|
|
|
|
|
||
|
|
Securities |
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|
|
Securities |
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||
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Underlying |
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Underlying |
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|
||
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Unexercised |
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Unexercised |
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|
|
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|
||
|
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Options (#) |
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|
|
Options (#) |
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|
Option Exercise |
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|
Option Expiration |
|||
Name |
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Exercisable |
|
|
|
Unexercisable |
|
|
Price ($) |
|
|
Date |
|||
Gregory A. Demopulos, M.D. |
|
|
281,163 |
|
(1) |
|
|
— |
|
|
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0.98 |
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|
12/11/16 |
|
|
|
612,244 |
|
(1) |
|
|
— |
|
|
|
0.98 |
|
|
12/11/16 |
|
|
|
102,040 |
|
(2) |
|
|
— |
|
|
|
2.45 |
|
|
12/29/17 |
|
|
|
215,000 |
|
(3) |
|
|
— |
|
|
|
6.31 |
|
|
04/06/20 |
|
|
|
110,000 |
|
(4) |
|
|
— |
|
|
|
6.31 |
|
|
04/06/20 |
|
|
|
260,000 |
|
(5) |
|
|
— |
|
|
|
4.10 |
|
|
01/08/22 |
|
|
|
252,083 |
|
(6) |
|
|
22,917 |
|
|
|
10.40 |
|
|
10/07/22 |
|
|
|
233,333 |
|
(9) |
|
|
116,667 |
|
|
|
9.37 |
|
|
09/25/23 |
|
|
|
16,666 |
|
(9) |
|
|
8,334 |
|
|
|
11.19 |
|
|
10/02/23 |
|
|
|
187,497 |
|
(11) |
|
|
262,503 |
|
|
|
11.58 |
|
|
10/29/24 |
Michael A. Jacobsen |
|
|
58,218 |
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(10) |
|
|
45,282 |
|
|
|
9.37 |
|
|
09/25/23 |
|
|
|
41,666 |
|
(11) |
|
|
58,334 |
|
|
|
11.58 |
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|
10/29/24 |
Marcia S. Kelbon, J.D., M.S. |
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|
143,200 |
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(7) |
|
|
— |
|
|
|
0.98 |
|
|
12/11/16 |
|
|
|
75,000 |
|
(3) |
|
|
— |
|
|
|
6.05 |
|
|
03/28/20 |
|
|
|
16,044 |
|
(8) |
|
|
— |
|
|
|
6.05 |
|
|
03/28/20 |
|
|
|
112,700 |
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(5) |
|
|
— |
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|
|
4.10 |
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01/08/22 |
|
|
|
82,500 |
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(6) |
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7,500 |
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|
|
10.40 |
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|
10/07/22 |
|
|
|
69,000 |
|
(9) |
|
|
34,500 |
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|
|
9.37 |
|
|
09/25/23 |
|
|
|
45,832 |
|
(11) |
|
|
64,168 |
|
|
|
11.58 |
|
|
10/29/24 |
(1) |
The shares subject to this option award vested on a monthly basis in equal amounts over a four-year period that began on February 28, 2005. |
(2) |
1/4 of the shares subject to this option award vested on December 30, 2008 and 1/48th of the shares subject to this option award vested each month thereafter. |
(3) |
The shares subject to this option award vested on a monthly basis in equal amounts over a four-year period that began on March 1, 2010. |
(4) |
The shares subject to this option award vested on a monthly basis in equal amounts over a four-year period that began on February 28, 2009. |
(5) |
The shares subject to this option award vested on a monthly basis in equal amounts over a four-year period that began on April 1, 2011. |
(6) |
The shares subject to this option award vest on a monthly basis in equal amounts over a four-year period that began on April 1, 2012. |
(7) |
The shares subject to this option award vested on a monthly basis in equal amounts over a four-year period that began on October 1, 2005. |
(8) |
The shares subject to this option award vested on a monthly basis in equal amounts over a four-year period that began on October 1, 2009. |
(9) |
The shares subject to this option award vest on a monthly basis in equal amounts over a four-year period that began on April 1, 2013. |
(10) |
1/4 of the shares subject to this option award vested on September 3, 2014 and 1/48th of the shares subject to this option award vest each month thereafter. |
(11) |
The shares subject to this option award vest on a monthly basis in equal amounts over a four-year period that began on April 1, 2014. |
20
2015 Option Exercises and Stock Vested
The following table shows certain information regarding option exercises by our named executive officers during the year ended December 31, 2015.
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Number of |
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|
|
|
|
|
|
|
Shares Acquired |
|
|
Value Realized on |
|
||
Name |
|
on Exercise (#) |
|
|
Exercise ($)(1) |
|
||
Gregory A. Demopulos, M.D. |
|
|
44,000 |
|
|
|
772,440 |
|
Michael A. Jacobsen |
|
|
— |
|
|
|
— |
|
Marcia S. Kelbon, J.D., M.S. |
|
|
44,202 |
|
|
|
596,998 |
|
(1) |
Represents the difference between the closing price of our common stock on the date of exercise and the exercise price of the option award. |
Potential Payments upon Termination or Change in Control
Pursuant to our employment agreement with Dr. Demopulos we are required to make payments to him upon termination of his employment in the circumstances described below. In addition, under the terms of our equity incentive plans, all of our named executive officers and key employees are entitled to acceleration of vesting of their option awards upon our change in control. These arrangements are discussed below.
Employment Agreement with Gregory A. Demopulos, M.D.
Overview. We entered into an employment agreement with Dr. Gregory A. Demopulos dated April 7, 2010 related to his service as our president and chief executive officer. Pursuant to the terms of his employment agreement, Dr. Demopulos is an at-will employee and was entitled to receive an initial annual base salary of $600,000, which our compensation committee reviews at least annually. In April 2014, our compensation committee increased Dr. Demopulos’ annual base salary to $669,500 from $650,000, effective as of April 2013. We may not reduce Dr. Demopulos’ annual base salary without his consent. Dr. Demopulos is entitled to participate in awards under our equity compensation and/or equity incentive plans at a level and on terms commensurate with his position and responsibilities, and no less favorable than those applicable to chief executive officers of peer companies as reasonably determined by the compensation committee, taking into account the recommendation of our independent compensation consultants. Dr. Demopulos also is entitled to participate in any employee benefit and fringe benefit plans that we make available to our executive employees, such as our equity compensation plans, 401(k) plan, disability and life insurance and company-paid health insurance. We also have agreed to allow Dr. Demopulos to maintain his status as a board-eligible orthopedic and hand and microvascular surgeon, which includes his performance of surgical procedures on a limited basis, and have agreed to pay related malpractice insurance and professional fees, which were $10,036 in 2015. We believe that Dr. Demopulos’ ability to maintain his standing as a practicing surgeon is beneficial to our corporate objectives including, for example, providing him with insight in determining the strategic direction of the company and our specific drug development programs as well as establishing relationships with key medical opinion leaders.
The employment agreement prohibits Dr. Demopulos from carrying on any business or activity, directly or indirectly, in direct competition with us or soliciting our employees to terminate their employment with us or to work with one of our competitors during his employment and for a period of up to two years following termination of his employment. In addition, the employment agreement prohibits him from soliciting or attempting to influence any of our customers or clients to purchase products from our competitors rather than our products.
The compensation due to Dr. Demopulos pursuant to his employment agreement in the event of the termination of his employment with us varies depending upon the nature of the termination.
21
Termination Without Cause or for Good Reason. Dr. Demopulos’ employment agreement provides that if we terminate his employment without “cause,” as defined below, or if he terminates his employment with us for “good reason,” as defined below, then until the earlier of (1) two years from the date of his termination and (2) his start date with a new employer that pays him an annual base salary at least equal to the annual base salary we paid to him prior to his termination (provided that if he terminates his employment for good reason because of a reduction in his annual base salary, then the annual base salary that will be measured will be the annual base salary we paid him prior to such reduction), we will be obligated to pay him on our regularly scheduled payroll dates on an annualized basis:
|
· |
the annual base salary he was receiving as of his termination, provided that if he terminates his employment for good reason because of a reduction in his annual base salary, then the annual base salary we will be obligated to pay him will be his annual base salary in effect prior to such reduction; plus |
|
· |
the greater of (1) the average annual bonus he received in the preceding two calendar years and (2) any bonus he would have been entitled to in the year of his termination as determined by our board of directors in good faith. |
In addition, if we terminate Dr. Demopulos’ employment without cause or if he terminates his employment with us for good reason, all of his unvested option awards will immediately vest and become exercisable until the maximum term of the respective option awards and all unvested restricted shares he holds will immediately vest. Dr. Demopulos and his eligible dependents may also continue to participate in all health plans we provide to our executive employees on the same terms as our employees for a period of up to two years from the date of his termination, unless his new employer provides comparable coverage.
“Cause” is defined under Dr. Demopulos’ employment agreement to mean:
|
· |
his willful misconduct or gross negligence in the performance of his duties, including his refusal to comply in any material respect with the legal directives of our board of directors so long as such directives are not inconsistent with his position and duties, and such refusal to comply is not remedied within 10 working days after written notice from the board of directors; |
|
· |
dishonest or fraudulent conduct that materially discredits us, a deliberate attempt to do an injury to us or conduct that materially discredits us or is materially detrimental to our reputation, including conviction of a felony; or |
|
· |
his material breach, if incurable, of any element of his confidential information and invention assignment agreement with us, including without limitation, his theft or other misappropriation of our proprietary information. |
Dr. Demopulos may terminate his employment for “good reason” if he terminates his employment with us within 120 days of the occurrence of any of the following events:
|
· |
any material diminution in his authority, duties or responsibilities; |
|
· |
any material diminution in his base salary; |
|
· |
we relocate his principal work location to a place that is more than 50 miles from our current location; or |
|
· |
we materially breach his employment agreement. |
If any of the above events have occurred as a result of our action, we will have 30 days from notice of such event from Dr. Demopulos to remedy the situation, in which case Dr. Demopulos will not be entitled to terminate his employment for good reason related to the event.
If Dr. Demopulos’ employment had been terminated without cause or if he had terminated his employment with good reason on December 31, 2015, he would have been entitled to receive an annual base salary of $669,500, payable on a bi-monthly basis over a period of up to two years from the date of termination. In addition, option awards with a value of $1.9 million would automatically vest upon his termination, which is the difference between $15.73, the closing trading price of our common stock on December 31, 2015, and the exercise price of the outstanding option awards held by Dr. Demopulos with an exercise price less of than $15.73, multiplied by the number of shares subject to each such option award that would have vested on his termination date.
Dr. Demopulos and his eligible dependents would also be entitled to participate in the health plans we provide to our employees for a period of up to two years from the date of his termination at a cost to us of approximately $13,179.
Termination for Cause, Voluntary Termination, Death or Disability. If we terminate Dr. Demopulos’ employment for cause, if he voluntarily terminates his employment with us other than for good reason, or if his employment is terminated as a result of his death or “disability,” as defined below, Dr. Demopulos will be entitled to receive payments for all earned but unpaid salary bonuses and vacation time, but he will not be entitled to any severance benefits.
22
“Disability” is defined under Dr. Demopulos’ employment agreement as his inability to perform his duties as the result of his incapacity due to physical or mental illness, and such inability, which continues for at least 120 consecutive calendar days or 150 calendar days during any consecutive 12-month period, if shorter, after its commencement, is determined to be total and permanent by a physician selected by us and our insurers and acceptable to Dr. Demopulos.
Second Amended and Restated 1998 Stock Option Plan and 2008 Equity Incentive Plan
Pursuant to our Second Amended and Restated 1998 Stock Option Plan, or 1998 Plan, and our 2008 Plan, in the event of a change in control, as separately defined in each equity plan, the vesting of option awards issued pursuant to such plans and held by our then-current employees, including those held by Dr. Demopulos, Mr. Jacobsen and Ms. Kelbon, will be accelerated to the extent of 50% of the remaining unvested shares. If there is no assumption or substitution of outstanding option awards by the successor corporation in the change in control, the option awards will become fully vested and exercisable immediately prior to the change in control. In addition, if within 12 months following a change in control Dr. Demopulos, Mr. Jacobsen, Ms. Kelbon or another significant employee is terminated without “cause” or as a result of a “constructive termination,” as such terms are defined below, any outstanding option awards held by him or her, as applicable, that we issued pursuant to the 1998 Plan or 2008 Plan will become fully vested and exercisable. The amounts under these plans that our named executive officers would have received under each of these scenarios appear in the table below. The 2008 Plan and 1998 Plan define key terms relating to the change in control provisions as follows:
|
· |
a “change in control” means a proposed sale of all or substantially all of our assets, or the merger of us with or into another corporation, or other change in control; |
|
· |
a termination for “cause” means a termination of an employee for any of the following reasons: (1) his or her willful failure to substantially perform his or her duties and responsibilities to us or a deliberate violation of a company policy; (2) his or her commission of any act of fraud, embezzlement, dishonesty or any other willful misconduct that has caused or is reasonably expected to result in material injury to us; (3) unauthorized use or disclosure by him or her of any proprietary information or trade secrets of ours or any other party to whom he or she owes an obligation of nondisclosure as a result of his or her relationship with us; or (4) his or her willful breach of any of his or her obligations under any written agreement or covenant with us; and |
|
· |
a “constructive termination” means the occurrence of any of the following events: (1) there is a material adverse change in an employee’s position causing such position to be of materially reduced stature or responsibility; (2) a reduction of more than 30% of an employee’s base compensation unless in connection with similar decreases of other similarly situated employees; or (3) an employee’s refusal to comply with our request to relocate to a facility or location more than 50 miles from our current location; provided that in order for an employee to be constructively terminated, he or she must voluntarily terminate his or her employment within 30 days of the applicable material change or reduction. |
Equity Acceleration Upon a Change in Control
The following table summarizes the value that Dr. Demopulos, Mr. Jacobsen and Ms. Kelbon would have derived from the acceleration of outstanding equity awards had a change in control (and certain other events, as applicable) occurred on December 31, 2015. The amounts below represent the difference between $15.73, the closing trading price of our common stock on December 31, 2015, and the exercise price of the option awards held by these individuals, all of which had an exercise price of less than $15.73, multiplied by the number of shares subject to such option awards that would have vested pursuant to the terms of the 2008 Plan and 1998 Plan on December 31, 2015 upon the occurrence of each of the events identified in the table below.
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Termination Without Cause or |
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Option Awards |
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Option Awards |
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Constructive Termination |
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|||
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Assumed by |
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Not Assumed |
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Within 12 Months of |
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Name |
|
Successor ($) |
|
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by Successor ($) |
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Change in Control ($) |
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|||
Gregory A. Demopulos, M.D. |
|
|
995,687 |
|
|
|
1,991,374 |
|
|
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1,991,374 |
|
Michael A. Jacobsen |
|
|
265,040 |
|
|
|
530,080 |
|
|
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530,080 |
|
Marcia S. Kelbon, J.D., M.S. |
|
|
262,846 |
|
|
|
525,692 |
|
|
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525,692 |
|
23
TRANSACTIONS WITH RELATED PERSONS
The following is a summary of transactions since January 1, 2015 to which we have been a party in which the amount involved exceeded $120,000 and in which any of our executive officers, directors or beneficial holders of more than five percent of our capital stock had or will have a direct or indirect material interest, other than compensation arrangements which are described elsewhere in this proxy statement.
Technology Transfer Agreements
We are party to a June 1994 technology transfer agreement with Gregory A. Demopulos, M.D. pursuant to which he irrevocably transferred to us all of his intellectual property rights in our PharmacoSurgery® platform. In December 2001, we entered into a second technology transfer agreement with Dr. Demopulos pursuant to which he irrevocably transferred to us all of his intellectual property rights in our Chondroprotective program, around which we have suspended activity due to resource prioritization but continue to maintain our related intellectual property rights. Other than his rights as a shareholder, Dr. Demopulos has not retained any rights to our PharmacoSurgery platform or Chondroprotective program, except that if we file for liquidation under Chapter 7 of the U.S. Bankruptcy Code or voluntarily liquidate or dissolve, other than in connection with a merger, reorganization, consolidation or sale of assets, Dr. Demopulos and another individual have the right to repurchase the PharmacoSurgery and Chondroprotective intellectual property at their respective then-current fair market values.
Indemnification Agreements
We have entered and expect to continue to enter into agreements to indemnify our directors, executive officers and other employees as determined by the board of directors. With certain exceptions, these agreements provide for indemnification for expenses including, among other things, attorneys’ fees, judgments, fines and settlement amounts incurred by any of these individuals in any action or proceeding relating to their service to Omeros.
Policies and Procedures for Related-Party Transactions
We have adopted a written policy that prohibits our executive officers, directors and director nominees and principal shareholders, including their immediate family members, from entering into a related-party transaction with us without the approval of our audit committee. Any request for us to enter into a transaction with an executive officer, director or director nominee, principal shareholder, or any of such persons’ immediate family members, in which such party had, has or will have a direct or indirect material interest and where the amount involved exceeds $120,000, other than certain excluded transactions including those involving compensation for services provided to us as an executive officer or director, must be presented to our audit committee for review, consideration and approval. All of our directors and executive officers are required to report to our audit committee any such related-party transaction. In considering the proposed related-party transaction, our audit committee will consider the relevant facts and circumstances available and deemed relevant to the audit committee, including, whether the transaction is fair to us, whether there are business reasons to enter into the transaction and whether the terms of the transaction would be similar if the transaction did not involve a related party, whether the transaction would impair the independence of a non-employee director, the materiality of the transaction and whether the transaction would present an improper conflict of interest between us and the related party.
24
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT
The following table sets forth certain information with respect to the beneficial ownership of our common stock at April 1, 2016, for: each person who we know beneficially owns more than five percent of our common stock; each of our directors; each of our named executive officers; and all of our directors and named executive officers as a group.
We have determined beneficial ownership in accordance with the rules of the SEC. Except as indicated by the footnotes below, we believe, based on the information furnished to us, that the persons and entities named in the table below have sole voting and investment power with respect to all shares of common stock that they beneficially own, subject to applicable community property laws. Applicable percentage ownership is based on 39,119,154 shares of common stock outstanding at April 1, 2016. In computing the number of shares of common stock beneficially owned by a person and the percentage ownership of that person, we deemed to be outstanding all shares of common stock subject to options held by that person that are currently exercisable or exercisable within 60 days of April 1, 2016. We did not deem these shares outstanding, however, for the purpose of computing the percentage ownership of any other person.
Unless otherwise indicated, the address of each person who owns more than five percent of our common stock listed in the table below is c/o Omeros Corporation, The Omeros Building, 201 Elliott Avenue West, Seattle, Washington 98119.
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Number of |
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Shares |
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Percent of Class |
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||
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Exercisable |
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Beneficially |
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Beneficially |
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|||
Name and Address of Beneficial Owner |
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Stock Options(1) |
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Owned(2) |
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Owned |
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|||
5% Security Holders: |
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|
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|
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|
|
|
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|
|
Ingalls & Snyder, LLC(3) |
|
|
— |
|
|
|
3,760,620 |
|
|
|
9.6 |
% |
BlackRock, Inc.(4) |
|
|
— |
|
|
|
2,554,983 |
|
|
|
6.5 |
% |
Cormorant Global Healthcare Master Fund, LP(5) |
|
|
— |
|
|
|
1,960,000 |
|
|
|
5.0 |
% |
Executive Officers and Directors: |
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|
|
|
|
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|
|
|
|
|
Gregory A. Demopulos, M.D. |
|
|
2,387,210 |
|
|
|
4,091,032 |
|
(6) |
|
9.9 |
% |
Michael A. Jacobsen |
|
|
144,102 |
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|
|
144,102 |
|
|
* |
|
|
Marcia S. Kelbon, J.D., M.S. |
|
|
522,810 |
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|
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686,407 |
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|
|
1.7 |
% |
Ray Aspiri |
|
|
10,000 |
|
|
|
237,178 |
|
(7) |
* |
|
|
Thomas J. Cable |
|
|
35,000 |
|
|
|
84,067 |
|
|
* |
|
|
Peter A. Demopulos, M.D. |
|
|
23,334 |
|
|
|
372,898 |
|
(8) |
|
1.0 |
% |
Arnold C. Hanish |
|
|
25,000 |
|
|
|
27,400 |
|
|
* |
|
|
Leroy E. Hood, M.D., Ph.D. |
|
|
35,000 |
|
|
|
89,390 |
|
|
* |
|
|
Rajiv Shah, M.D. |
|
|
— |
|
|
|
0 |
|
|
* |
|
|
All executive officers and directors as a group (9 persons) |
|
|
3,182,456 |
|
|
|
5,732,474 |
|
|
|
13.6 |
% |
* |
Less than 1% |
(1) |
Represents shares that could be purchased pursuant to the exercise of option awards vested as of and within 60 days of April 1, 2016. |
(2) |
Represents outstanding shares plus the options set forth in the previous column. |
(3) |
Derived from amount reported in Amendment No. 4 to Schedule 13G filed with the SEC on February 5, 2016. The address of Ingalls & Snyder, LLC is 1325 Avenue of the Americas, New York, NY 10019. The Schedule 13G/A indicates that Ingalls & Snyder, LLC has shared dispositive power, but lacks voting power, over the shares. The Schedule 13G/A filed by the reporting person provides information as of December 31, 2015 and, consequently, the beneficial ownership of the reporting person may have changed between December 31, 2015 and the date of this proxy statement. |
(4) |
Derived from amount reported in Amendment No. 1 to Schedule 13G filed with the SEC on January 27, 2016. The address of BlackRock, Inc. is 55 East 52nd Street, New York, NY 10055. The Schedule 13G/A indicates that BlackRock, Inc. has sole voting power over 2,485,970 shares of common stock and sole dispositive power over 2,554,983 shares of common stock. The Schedule 13G/A filed by the reporting person provides information as of December 31, 2015 and, consequently, the beneficial ownership of the reporting person may have changed between December 31, 2015 and the date of this proxy statement. |
(5) |
Derived from amount reported in a Schedule 13G filed with the SEC on September 28, 2015 by Cormorant Global Healthcare Master Fund, LP, or Fund, Cormorant Global Healthcare GP, LLC, or GP, Cormorant Asset Management, LLC, or Manager, and Bihua Chen, or Chen. According to the Schedule 13G/A, GP serves as the general partner of the Fund, Manager serves as the investment manager of the Fund and Chen serves as the managing member of GP and Manager. Each of Fund, GP, Manager and Chen disclaims beneficial ownership of such shares, except to the extent of its or his pecuniary interest therein. The address of Fund, GP, Manager and Chen is 200 Clarendon Street, 52nd Floor, Boston, MA 02116. The Schedule 13G filed by the reporting person provides information as of September 22, 2015 and, consequently, the beneficial ownership of the reporting person may have changed between September 22, 2015 and the date of this proxy statement. |
25
(6) |
Dr. Demopulos has pledged 1,703,822 of his outstanding shares of common stock as collateral for a line of credit as described in “Hedging and Pledging Policy” above in this proxy statement. |
(7) |
Includes 186,872 shares of common stock held by Aspiri Enterprises LLC, of which Mr. Aspiri is the managing partner and a member. |
(8) |
Includes 164,382 shares of common stock held by The Demopulos Family Trust, of which Dr. Peter A. Demopulos is the trustee and a beneficiary along with his mother and sister. Such shares are pledged as collateral for a line of credit as described in “Hedging and Pledging Policy” above in this proxy statement. Dr. Peter A. Demopulos disclaims beneficial ownership of the shares held by The Demopulos Family Trust except to the extent of his pecuniary interest therein. In addition, 140,000 of Dr. Peter A. Demopulos’ outstanding shares of common stock are being pledged as collateral for a line of credit as described in “Hedging and Pledging Policy” above in this proxy statement. |
SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE
Section 16(a) of the Exchange Act requires our officers and directors and persons who own more than 10% of a registered class of our equity securities to file reports of ownership on Form 3 and changes in ownership on Form 4 or Form 5 with the SEC. Such officers, directors and 10% shareholders are also required to furnish us with copies of all Section 16(a) forms they file. Based solely on our review of the copies of such forms we received, we believe that during the 2015 fiscal year all Section 16(a) filing requirements applicable to our officers, directors and 10% shareholders were satisfied.
PROPOSAL 2 — RATIFICATION OF OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
The audit committee of our board of directors has appointed Ernst & Young LLP as our independent registered public accounting firm for the current year and the board of directors is asking our shareholders to ratify that appointment. Although current laws, rules and regulations, as well as the charter of the audit committee, require our independent registered public accounting firm to be engaged, retained and supervised by the audit committee, the board considers the selection of the independent registered public accounting firm to be an important matter of shareholder concern and is submitting the selection of Ernst & Young for ratification by shareholders as a matter of good corporate practice. If the shareholders do not ratify the selection of Ernst & Young as our independent registered public accounting firm, the audit committee will consider this vote in determining whether or not to continue the engagement of Ernst & Young. If the shareholders do ratify the selection of Ernst & Young as our independent registered public accounting firm, the audit committee may nonetheless select a different auditing firm at any time during the year if it determines that such a change would be in our best interests. Representatives of Ernst & Young are expected to be present at the 2016 Annual Meeting, will have an opportunity to make a statement if they so desire and will be available to respond to appropriate questions.
THE BOARD OF DIRECTORS RECOMMENDS THAT SHAREHOLDERS
VOTE FOR THE RATIFICATION OF THE APPOINTMENT OF
ERNST & YOUNG LLP AS OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
Information Regarding our Independent Registered Public Accounting Firm
Fees for professional services provided by Ernst & Young, our independent auditors, in each of the last two fiscal years, in each of the following categories (in thousands) are:
|
|
2015 |
|
|
2014 |
|
||
Audit Fees |
|
$ |
649 |
|
|
$ |
652 |
|
Audit-Related Fees |
|
|
— |
|
|
|
— |
|
Tax Fees |
|
53 |
|
|
48 |
|
||
All Other Fees |
|
|
— |
|
|
|
— |
|
|
|
$ |
702 |
|
|
$ |
700 |
|
Audit Fees
Consists of fees associated with the annual audit of our financial statements, the reviews of our interim financial statements and quarterly reports on Form 10-Q and the issuance of consents and comfort letters in connection with registration statements.
26
Consists of fees associated with assurance and related services that are reasonably related to the performance of the audit or review of our financial statements including accounting consultations.
Tax Fees
Consists of fees associated with federal income tax compliance, tax advice and tax planning.
All Other Fees
Consists of fees associated with permitted corporate finance assistance and permitted advisory services, none of which were provided by our independent auditors during the last two fiscal years.
Audit Committee Pre-Approval Policy
The audit committee must pre-approve all services to be performed for us by Ernst & Young. Pre-approval is granted usually at regularly scheduled meetings of the audit committee. If unanticipated items arise between meetings of the audit committee, the audit committee has delegated authority to the chairman of the audit committee to pre-approve services, in which case the chairman communicates such pre-approval to the full audit committee at its next scheduled meeting. During 2015 and 2014, all services billed by Ernst & Young were pre-approved by the audit committee in accordance with this policy.
Audit Committee Report
In connection with the audited consolidated financial statements of Omeros Corporation for the fiscal year ended December 31, 2015, the audit committee of the board of directors has:
|
· |
reviewed and discussed with management Omeros’ audited consolidated financial statements as of and for the year ended December 31, 2015; |
|
· |
discussed with Ernst & Young LLP the matters required to be discussed under Public Company Accounting Oversight Board, or PCAOB, Auditing Standard No. 16, Communications with Audit Committees; |
|
· |
received the written disclosures and the letter from Ernst & Young LLP required by PCAOB Rule 3526 (Communications with Audit Committees Concerning Independence), and has discussed with Ernst & Young LLP its independence; and |
|
· |
based on the foregoing review and discussions, recommended to the board of directors that the audited consolidated financial statements be included in Omeros’ Annual Report on Form 10-K for the fiscal year ended December 31, 2015 for filing with the U.S. Securities and Exchange Commission. |
AUDIT COMMITTEE |
Arnold C. Hanish, Chairman |
Ray Aspiri |
Thomas J. Cable |
Obtaining an Annual Report on Form 10-K
The 2015 Annual Report on Form 10-K and the exhibits filed with it are available on our investor relations website at investor.omeros.com. Upon written request by any beneficial shareholder or shareholder of record, we will furnish, without charge, a copy of the 2015 Annual Report on Form 10-K, including the financial statements and the related footnotes. Requests should be made in writing addressed to: Omeros Corporation, The Omeros Building, 201 Elliott Avenue West, Seattle, WA 98119, Attn: Investor Relations. We will charge you for our copying costs if exhibits to the 2015 Annual Report on Form 10-K are requested.
27
Our board of directors is not aware of any other matters to be presented at the 2016 Annual Meeting. If, however, any other matter should properly come before the 2016 Annual Meeting, the enclosed proxy card confers discretionary authority with respect to such matter.
By Order of the Board of Directors, |
|
|
Marcia S. Kelbon |
Vice President, Patent |
General Counsel and Secretary |
April 22, 2016
YOUR VOTE IS IMPORTANT
Whether or not you plan to attend the 2016 Annual Meeting, we encourage you to vote in advance of the meeting to assure your representation at the meeting. You may vote prior to the 2016 Annual Meeting by mailing the proxy card in the enclosed postage-prepaid envelope, by telephone or via the Internet in accordance with the instructions on your proxy card. Even if you vote in advance of the 2016 Annual Meeting, you may still vote in person if you attend the meeting. Please note, however, that if your shares are held of record by a broker, bank or other nominee and you wish to vote at the 2016 Annual Meeting, you must obtain from the record holder a proxy card issued in your name.
28
. MMMMMMMMMMMM OMEROS CORPORATION MMMMMMMMM IMPORTANT ANNUAL MEETING INFORMATION 000004 ENDORSEMENT_LINE______________ SACKPACK_____________ MR A SAMPLE DESIGNATION (IF ANY) ADD 1 ADD 2 ADD 3 ADD 4 ADD 5 ADD 6 Using a black ink pen, mark your votes with an X as shown in Xthis example. Please do not write outside the designated areas. MMMMMMMMMMMMMMM C123456789 000000000.000000 ext 000000000.000000 ext 000000000.000000 ext 000000000.000000 ext 000000000.000000 ext 000000000.000000 ext Electronic Voting Instructions Available 24 hours a day, 7 days a week! Instead of mailing your proxy, you may choose one of the voting methods outlined below to vote your proxy. VALIDATION DETAILS ARE LOCATED BELOW IN THE TITLE BAR. Proxies submitted by the Internet or telephone must be received by11:59 PM, Eastern Time, on June 8, 2016. Vote by Internet • Go to www.envisionreports.com/OMER • Or scan the QR code with your smartphone • Follow the steps outlined on the secure website Vote by telephone • Call toll free 1-800-652-VOTE (8683) within the USA, US territories & Canada on a touch tone telephone • Follow the instructions provided by the recorded message Annual Meeting Proxy Card 1234 5678 9012 345 • IF YOU HAVE NOT VOTED VIA THE INTERNET OR TELEPHONE, FOLD ALONG THE PERFORATION, DETACH AND RETURN THE BOTTOM PORTION IN THE ENCLOSED ENVELOPE. • A Proposals — The Board of Directors recommends a vote FOR all the nominees listed and FOR Proposal 2. 1. Election of Directors: 01 - Ray Aspiri 02 - Arnold C. Hanish 03 - Rajiv Shah, M.D. +Mark here to vote Mark here to WITHHOLD For All EXCEPT - To withhold authority to vote for any FOR all nominees vote from all nominees nominee(s), write the name(s) of such nominee(s) below. For Against Abstain 2. Ratification of Ernst & Young LLP as independent 3. In their discretion, the proxies are authorized to vote upon such registered public accounting firm for 2016. other business as may properly come before the meeting. B Non-Voting Items Change of Address — Please print new address below. Comments — Please print your comments below. Authorized Signatures — This section must be completed for your vote to be counted. — Date and Sign Below NOTE: Please sign as name appears hereon. Joint owners should each sign. When signing as attorney, executor, administrator, trustee or guardian, please give full title as such. Date (mm/dd/yyyy) — Please print date below. Signature 1 — Please keep signature within the box. Signature 2 — Please keep signature within the box. MR A SAMPLE (THIS AREA IS SET UP TO ACCOMMODATE C 1234567890 J N T 140 CHARACTERS) MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND 1UPX 2759021 MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND MMMMMMM + 02BSXD
Attention Internet Users! You can now access your shareholder information on the following secure Internet site: www.computershare.com/investor Step 1: Register (1st time users only) Step 3: View your account details and perform multiple transactions, such as: • View account balances • Change your address • View transaction history • View electronic shareholder communications Step 2: Log in (Returning users) • View payment history • Buy or sell shares Enter your User ID and Password and click the Login button. • View stock quotes • Check replacements If you are not an Internet user and wish to contact Omeros Corporation you may use one of the following methods: Call: 866-282-4938 Write: Omeros Corporation, c/o Computershare, P.O. Box 43101, Providence, RI 02940 Important notice regarding the Internet availability of proxy materials for the 2016 Annual Meeting of Shareholders. The Proxy Statement and the 2015 Annual Report to Shareholders are available at: www.envisionreports.com/OMER • IF YOU HAVE NOT VOTED VIA THE INTERNET OR TELEPHONE, FOLD ALONG THE PERFORATION, DETACH AND RETURN THE BOTTOM PORTION IN THE ENCLOSED ENVELOPE. • Proxy — OMEROS CORPORATION PROXY FOR 2016 ANNUAL MEETING OF SHAREHOLDERS – JUNE 9, 2016 OMEROS CORPORATION THIS PROXY IS SOLICITED BY THE BOARD OF DIRECTORS The undersigned shareholder of Omeros Corporation hereby appoints Gregory A. Demopulos, M.D. and Marcia S. Kelbon, and each of them, with power to act without the other and with power of substitution, as proxies and attorneys-in-fact and hereby authorizes them to represent and vote, as provided on the other side, all the shares of Omeros Corporation Common Stock which the undersigned is entitled to vote, and, in their discretion, to vote upon such other business as may properly come before the 2016 Annual Meeting of Shareholders of Omeros to be held at the World Trade Center Seattle, 2200 Alaskan Way, Suite 410, Seattle, Washington 98121 on June 9, 2016, at 10:00 a.m. local time, or at any adjournment or postponement thereof, with all powers that the undersigned would possess if present at the Annual Meeting. The undersigned hereby acknowledges receipt of the Company’s Proxy Statement in connection with the Annual Meeting and hereby revokes any proxy or proxies previously given. THIS PROXY WHEN PROPERLY EXECUTED WILL BE VOTED IN THE MANNER DIRECTED HEREIN BY THE UNDERSIGNED SHAREHOLDER AND IN ACCORDANCE WITH THE DISCRETION OF THE PROXIES AS TO ANY OTHER MATTERS THAT ARE PROPERLY PRESENTED. UNLESS DIRECTION IS GIVEN, THIS PROXY WILL BE VOTED AS FOLLOWS: “FOR” ALL NOMINEES LISTED IN PROPOSAL 1, “FOR” PROPOSAL 2 AND IN THE DISCRETION OF THE PROXIES ON SUCH OTHER MATTERS AS MAY PROPERLY COME BEFORE THE MEETING, INCLUDING, AMONG OTHER THINGS, CONSIDERATION OF ANY MOTION MADE FOR ADJOURNMENT OF THE MEETING. (Continued and to be marked, dated and signed, on the other side)