UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                         -------------------------------

                                    FORM 8-K

                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934


Date of report (Date of earliest event reported) February 12, 2004
                                                 -------------------------------


                           SENESCO TECHNOLOGIES, INC.
--------------------------------------------------------------------------------
               (Exact Name of Registrant as Specified in Charter)


        Delaware                      001-31326                  84-1368850
--------------------------------------------------------------------------------
(State or Other Jurisdiction    (Commission File Number)        (IRS Employer
    of Incorporation)                                        Identification No.)



303 George Street, Suite 420, New Brunswick, New Jersey              08901
--------------------------------------------------------------------------------
(Address of Principal Executive Offices)                           (Zip Code)



Registrant's telephone number, including area code       (732) 296-8400
                                                  ------------------------------




--------------------------------------------------------------------------------
          (Former Name or Former Address, if Changed Since Last Report)






ITEM 5.  OTHER EVENTS.


     In  connection  with the private  placement  (the "Private  Placement")  of
Senesco  Technologies,  Inc., a Delaware corporation (the "Company"),  which was
previously  reported  on the  Company's  Current  Report on Form  8-K,  filed on
February 3, 2004, the Company entered into a Securities  Purchase Agreement (the
"Securities  Purchase Agreement") with an additional  institutional  investor on
February 12, 2004, pursuant to which the Company issued and sold an aggregate of
approximately  485,000 units at $2.37 per unit,  comprised of one share of newly
issued  common  stock,  $0.01 par value per share (the  "Common  Stock"),  and a
five-year  warrant to  purchase  0.35 of a share of Common  Stock at an exercise
price of $3.79 per share. Thereafter, on February 12, 2004, the Company and such
additional  investor  entered into  Amendment No. 1 to the  Securities  Purchase
Agreement,  pursuant  to which the Company  revised the terms of the  Securities
Purchase  Agreement to issue, in lieu of the warrant to purchase 0.35 of a share
of Common  Stock,  a warrant to  purchase  0.50 of a share of Common  Stock.  In
connection  therewith,  the  Company  will issue to each prior  investor  in the
Private  Placement,  who had already been issued a warrant to purchase 0.35 of a
share of Common  Stock for each share of Common  Stock  purchased in the Private
Placement, an additional warrant to purchase 0.15 of a share of Common Stock for
each share of Common Stock previously purchased by such investor.

     On February 12, 2004, the Company and the additional  investor also entered
into a Registration Rights Agreement (the "Registration  Rights Agreement"),  as
amended by Amendment No. 1 to the  Registration  Rights  Agreement,  pursuant to
which, among other things, the Company will pay to the investor, in cash, check,
or by wire transfer,  one and one-half percent (1.5%) of the aggregate  purchase
price  paid by the  investor  for all  shares  and  warrants  sold to each  such
investor  in the event  that the  Company  fails to  respond  in  writing to any
comments of the Securities and Exchange  Commission  regarding the  Registration
Statement within ten (10) business days following  receipt thereof.  The Company
will also provide this right to each prior investor in the Private Placement.

     The  securities  sold in this private  placement  have not been  registered
under the Securities Act of 1933, as amended (the "Securities Act"), and may not
be  offered  or  sold  in the  United  States  in the  absence  of an  effective
registration statement or exemption from the registration requirements under the
Securities  Act.  In  accordance  with  the  terms  of the  Registration  Rights
Agreement,  the Company has agreed to file a resale  registration  statement  on
Form S-3 by March 18, 2004 to  register,  pursuant to the  Securities  Act,  the
shares of Common  Stock and  shares of  Common  Stock  underlying  the  warrants
acquired by the investors.

     The Securities  Purchase  Agreement and the  Registration  Rights Agreement
were previously  filed as exhibits to the Company's  Current Report on Form 8-K,
filed on February 3, 2004.  A complete  copy of each of  Amendment  No. 1 to the
Securities  Purchase  Agreement,  Amendment  No.  1 to the  Registration  Rights
Agreement,  and the related press release of the Company,  are filed herewith as
Exhibits 10.3,  10.4 and  99.1,  respectively,  and are  incorporated  herein by
reference.  The foregoing descriptions of: (i) Amendment No. 1 to the Securities
Purchase  Agreement;  (ii) Amendment No. 1 to the Registration Rights Agreement;
and (iii) the press release and any other documents or filings referenced herein
are  qualified in their  entirety by reference  to such  exhibits,  documents or
filings.


                                      -2-



ITEM 7.  FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.


     (c) Exhibits.

         Exhibit No.           Description of Exhibits
         -----------           -----------------------

            10.1    Form of  Securities  Purchase  Agreement  by and between the
                    Company  and certain  accredited  investors  (with  attached
                    schedule  of parties  and terms  thereto).  Incorporated  by
                    reference to the Company's Current Report on Form 8-K, filed
                    on February 3, 2004.

            10.2    Form of  Registration  Rights  Agreement  by and between the
                    Company  and certain  accredited  investors  (with  attached
                    schedule  of parties  and terms  thereto).  Incorporated  by
                    reference to the Company's Current Report on Form 8-K, filed
                    on February 3, 2004.

            10.3    Amendment No. 1 to the Securities  Purchase Agreement by and
                    between the Company and Crestview Capital Master, L.L.C.

            10.4    Amendment No. 1 to the Registration  Rights Agreement by and
                    between the Company and Crestview Capital Master, L.L.C.

            99.1    Press  Release  dated  February  13,  2004,  announcing  the
                    additional investment under the Private Placement.





                                      -3-



                                    SIGNATURE
                                    ---------

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.



                                             SENESCO TECHNOLOGIES, INC.



                                             By:    /s/ Joel Brooks
                                                --------------------------------
                                                Name:  Joel Brooks
                                                Title:  Chief Financial Officer


February 13, 2004