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MAIA Biotechnology (MAIA) to Showcase Groundbreaking Telomere-Targeting Cancer Treatments at BIO International Convention 2024

MAIA Biotechnology (MAIA) to Showcase Groundbreaking Telomere-Targeting Cancer Treatments at BIO International Convention 2024
Biotech Stocks In Focus
MAIA Chairman and CEO Vlad Vitoc, M.D. will deliver a presentation featuring up-to-date findings from the Company’s Phase 2 THIO-101 clinical trial evaluating THIO sequenced with the immune checkpoint inhibitor (CPI) cemiplimab (Libtayo®) in advanced non-small cell lung cancer (NSCLC).

MAIA Biotechnology, Inc. (NYSE American: MAIA) is capturing the attention of traders and investors with its innovative approaches to cancer treatment, focusing on telomere-targeting therapies. The company is scheduled to present at the BIO International Convention 2024 in San Diego, California, from June 3-6. This major event attracts over 20,000 industry leaders worldwide, providing a platform for discussing advancements in biotechnology.

At the convention, MAIA's CEO, Dr. Vlad Vitoc, will showcase the latest findings from the Phase 2 THIO-101 clinical trial. This trial is particularly significant as it assesses THIO—a novel anticancer agent—in combination with the immune checkpoint inhibitor cemiplimab, targeting advanced non-small cell lung cancer (NSCLC). THIO functions by inducing telomeric DNA damage and boosting cancer-specific immune responses, potentially offering a new pathway for cancer treatment where previous options have failed.

The company's recent stock performance has significantly boosted investor interest. MAIA's shares have surged over 300% year-to-date as of the end of May 2024. Analysts remain optimistic, setting a target price of $14.00 for the stock, which implies a substantial upside of nearly 195% from its recent trading price of $4.75.

As MAIA Biotechnology progresses through its clinical trials and presents its findings at high-profile events like the BIO International Convention, it is emerging as a transformative force in the biotechnology sector, particularly in oncology. The developments in its THIO program could significantly enhance its market valuation and impact the therapeutic landscape for cancers such as NSCLC.

About THIO

THIO (6-thio-dG or 6-thio-2’-deoxyguanosine) is a pioneering investigational telomere-targeting agent in clinical development to assess its efficacy in Non-Small Cell Lung Cancer (NSCLC). Telomeres and the enzyme telomerase are crucial for the survival of cancer cells and their resistance to current treatments. THIO induces telomerase-dependent telomeric DNA alterations, triggering DNA damage responses and selective cancer cell death. Accumulation of THIO-damaged telomeric fragments in cytosolic micronuclei activates both innate (cGAS/STING) and adaptive (T-cell) immune responses. Sequential treatment with THIO and PD-(L)1 inhibitors has shown profound and lasting tumor regression in advanced cancer models, establishing cancer type-specific immune memory. THIO is currently being developed as a second or later line treatment for NSCLC in patients who have progressed beyond standard care regimens of existing checkpoint inhibitors.

About THIO-101, a Phase 2 Clinical Trial

THIO-101 is a multicenter, open-label, dose-finding Phase 2 clinical trial. It is the first study designed to evaluate THIO’s antitumor activity when followed by PD-(L)1 inhibition. The trial tests the hypothesis that low doses of THIO administered prior to cemiplimab (Libtayo®) will enhance and prolong the immune response in patients with advanced NSCLC who previously did not respond or developed resistance and progressed after first-line treatment containing another checkpoint inhibitor. The primary objectives of the trial are to evaluate the safety and tolerability of THIO as both an anticancer compound and a priming immune activator, and to assess its clinical efficacy using Overall Response Rate (ORR) as the primary clinical endpoint. Treatment with cemiplimab followed by THIO has been generally well-tolerated in a heavily pre-treated population. For more information on this Phase II trial, please visit ClinicalTrials.gov using the identifier NCT05208944.

As MAIA Biotechnology Inc (NYSE: MAIA) gears up to showcase its latest advancements at the BIO International Convention 2024, the company remains a focal point of interest within the investment community, thanks to its pioneering work in cancer treatment. The continued development and promising early results of its telomere-targeting agent, THIO, in combination with existing treatments, suggest potential breakthroughs in the management of non-small cell lung cancer. With a stock price that reflects growing investor confidence and a clinical trajectory that could lead to significant advancements in oncology, MAIA Biotechnology stands at the cusp of potentially reshaping cancer therapy. Looking ahead, the outcomes of the ongoing THIO-101 Phase 2 trial and subsequent presentations will be critical in determining the company's role in advancing cancer treatment and its long-term impact on patient care. As such, MAIA represents not just a significant investment opportunity but also a beacon of hope for advancements in the treatment of one of the most challenging diseases facing humanity.

Several companies have recently emerged as top gainers in the stock market. Avalon Globocare Corp (NASDAQ: ALBT) led the pack with an extraordinary 316.95% increase, closing at $1.23 with a trading volume of 157.88 million shares. Affimed NV (NASDAQ: AFMD) followed with a 68.51% rise to $7.33, accompanied by 30.76 million shares traded. Bio Path Holdings Inc (NASDAQ: BPTH) saw a significant 56.80% gain, reaching $3.23 with a volume of 56.79 million shares. Structure Therapeutics Inc (NASDAQ: GPCR) stock climbed 54.21% to $52.74, with 11.68 million shares traded. Four Seasons Education (Cayman) Inc (NYSE: FEDU) and Microbot Medical Inc (NASDAQ: MBOT) also posted impressive gains, with FEDU increasing by 38.63% to $14.75 on a volume of 23.35 thousand shares, and MBOT rising by 38.00% to $1.38, with 150.65 million shares traded

Disclaimer: This blog post is for informational purposes only and does not constitute financial advice or an endorsement of MAIA or its strategies. FOR EDUCATIONAL AND INFORMATION PURPOSES ONLY; NOT INVESTMENT ADVICE. Please ensure to fully read and comprehend our disclaimer found at https://investorbrandmedia.com/disclaimer/. InvestorBrandMedia.com has been compensated five hundred dollars by a 3rd party Bullzeyemedia LLC for content distribution services on MAIA for June 4th. We own zero shares of MAIA. InvestorBrandMedia.com is neither an investment advisor nor a registered broker. No current owner, employee, or independent contractor of InvestorBrandMedia.com is registered as a securities broker-dealer, broker, investment advisor, or IA representative with the U.S. Securities and Exchange Commission, any state securities regulatory authority, or any self-regulatory organization. This article may contain forward-looking statements as defined under Section 27A of the Securities Act of 1933 and 21E of the Exchange Act of 1934. These statements, often incorporating terms like “believes,” “anticipates,” “estimates,” “expects,” “projects,” “intends,” or similar expressions about future performance or conduct, are based on present expectations, estimates, and projections, and are not historical facts. They carry various risks and uncertainties that may result in significant deviation from the anticipated results or events. Past performance does not guarantee future results.InvestorBrandMedia.com does not commit to updating forward-looking statements based on new information or future events. Readers are encouraged to review all public SEC filings made by the profiled companies at https://www.sec.gov/edgar/searchedgar/companysearch. It is always important to conduct thorough due diligence and exercise caution in trading.InvestorBrandMedia.com is not managed by a licensed broker, a dealer, or a registered investment adviser. The content here is purely informational and should not be taken as investment advice. The Private Securities Litigation Reform Act of 1995 provides investors a safe harbor regarding forward-looking statements. Any statement that projects, foresees, expects, anticipates, estimates, believes, or understands certain actions to possibly occur are not historical facts and may be forward-looking statements. These statements are based on expectations, estimates, and projections that could cause actual results to differ greatly from those anticipated. Investing in micro-cap and growth securities is speculative and entails a high degree of risk, potentially leading to a total or substantial loss of investment. Please note that no content published here constitutes a recommendation to buy or sell a security. It is solely informational, and you should not construe it as legal, tax, investment, financial, or other advice. No content in this article constitutes an offer or solicitation by InvestorBrandMedia.com or any third-party service provider to buy or sell securities or other financial instruments. The content in this article does not address the circumstances of any specific individual or entity and does not constitute professional and/or financial advice. InvestorBrandMedia.com is not a fiduciary by virtue of any person’s use of or access to this content.

Sources:

https://finance.yahoo.com/news/maia-biotechnology-present-bio-international-123700141.html

https://www.tipranks.com/stocks/maia/forecast

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